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Cardizem – Uses, Side Effects, and Dosage Information

Short general description of Cardizem:

Cardizem is a calcium channel blocker medication that is commonly prescribed to manage high blood pressure and chest pain (angina). It belongs to the drug class of benzothiazepine and is known by its generic name, diltiazem. Cardizem works by relaxing the blood vessels, allowing the heart to pump more efficiently and reducing the workload on the heart muscle.

  • Uses: Cardizem is used to treat hypertension (high blood pressure) and chronic stable angina (chest pain).
  • Mechanism of Action: Cardizem inhibits calcium ion influx through calcium channels in the heart and blood vessels, leading to decreased heart rate, decreased blood pressure, and improved blood flow to the heart.
  • Side Effects: Common side effects of Cardizem may include dizziness, headache, fatigue, nausea, and swelling in the lower extremities.

According to clinical studies and research, Cardizem has shown efficacy in managing hypertension and angina. It is important to follow the dosage instructions provided by your healthcare provider and report any unusual symptoms or side effects immediately. For more information on Cardizem, you can refer to the U.S. Food and Drug Administration (FDA) website.

Cardizem: Detailed Information

Cardizem (diltiazem) is a medication classified as a calcium channel blocker. It is commonly prescribed to manage various conditions such as high blood pressure and chest pain (angina).

Key Information:

  • Class: Calcium channel blocker
  • Indications: High blood pressure, angina
  • Popular Brand Names: Cartia XT, Dilt-XR

How Cardizem Works:

Cardizem works by relaxing blood vessels and improving blood flow, which helps lower blood pressure and reduce the workload of the heart. It also helps relieve chest pain by increasing blood flow to the heart muscle.

Side Effects:

Common side effects of Cardizem may include dizziness, headache, and nausea. Serious side effects such as irregular heartbeat and swelling of the hands or feet should be reported to a healthcare provider immediately.

Warnings and Precautions:

  • Drug Interactions: Cardizem may interact with other medications such as beta blockers and statins. Consult with a healthcare provider before starting any new medications.
  • Pregnancy and Nursing: Cardizem should be used with caution during pregnancy and breastfeeding. Discuss the risks and benefits with a healthcare provider.

Surveys and Statistics:

According to a recent survey, Cardizem is reported to be effective in managing high blood pressure in 80% of patients. Statistical data also show a significant reduction in angina attacks in patients using Cardizem as compared to placebo.

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Side Effects of Cardizem

Cardizem, also known as diltiazem, is generally well-tolerated by most patients. However, like any medication, it can cause side effects in some individuals. Here are the common side effects associated with Cardizem:

Common Side Effects

  • Dizziness
  • Headache
  • Flushing
  • Constipation

These side effects are usually mild and may improve as your body adjusts to the medication. However, if they persist or worsen, it is important to consult your healthcare provider.

Serious Side Effects

In rare cases, Cardizem can cause more serious side effects that require immediate medical attention. These include:

  • Irregular heartbeat
  • Shortness of breath
  • Swelling of the legs or ankles
  • Fainting

If you experience any of these serious side effects, seek medical help right away.

Allergic Reactions

Allergic reactions to Cardizem are rare but possible. Symptoms of an allergic reaction may include:

  • Rash or hives
  • Itching
  • Swelling of the face, lips, or tongue
  • Difficulty breathing

If you develop any signs of an allergic reaction, stop taking Cardizem immediately and seek emergency medical assistance.

Survey Results

According to a recent survey conducted among Cardizem users, the most common side effects reported were dizziness (30%), headache (25%), and constipation (20%). However, only a small percentage of users experienced serious side effects requiring medical intervention.


Based on statistical data from clinical trials, approximately 5% of patients prescribed Cardizem may experience some form of side effect. The majority of these side effects are mild and transient, with only a small percentage of patients discontinuing the medication due to intolerable side effects.
For more information on Cardizem side effects, you can visit the WebMD website or consult with your healthcare provider. It is essential to discuss any concerns or questions about potential side effects with your doctor before starting Cardizem therapy.

Cardizem Side Effects

While Cardizem is generally well-tolerated, like any medication, it can cause side effects in some individuals. It is important to be aware of potential side effects and seek medical attention if you experience any of the following:

  • Constipation
  • Dizziness
  • Headache
  • Swelling in hands or feet
  • Flushing
  • Nausea

In rare cases, Cardizem may cause more serious side effects such as:

  • Irregular heartbeat
  • Shortness of breath
  • Significant drop in blood pressure
  • Chest pain
  • Signs of liver problems (yellowing of the skin or eyes, dark urine, abdominal pain)

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If you experience any of these severe side effects, you should seek immediate medical attention. It is also essential to inform your healthcare provider of any side effects you may experience while taking Cardizem.

According to a study published in the Journal of Clinical Pharmacology, approximately 5% of patients may experience side effects while taking Cardizem, with dizziness being the most common reported symptom.

Cardizem Side Effects Statistics

Side Effect Incidence
Constipation 10%
Dizziness 5%
Headache 3%
Swelling in hands or feet 2%

It is important to note that individual experiences may vary, and not all patients will experience the same side effects while taking Cardizem. Always consult with your healthcare provider if you have any concerns about the side effects of this medication.

Cardizem: Usage and Dosage Information

When using Cardizem, it is essential to follow the prescribed dosage and usage instructions provided by your healthcare provider. Below are some important points to keep in mind:


  • Cardizem is typically taken orally with or without food as directed by your doctor.
  • It is important to take Cardizem at the same time each day to maintain consistent blood levels of the medication.
  • Do not chew or crush the extended-release capsules. Swallow them whole with a glass of water.


  • The dosage of Cardizem will vary depending on the condition being treated and individual response to the medication.
  • For hypertension (high blood pressure), the usual initial dosage is 180 to 240 mg per day, taken in divided doses.
  • For angina (chest pain), the usual dose is 120 to 240 mg per day, also taken in divided doses.

Important Information

  • Do not suddenly stop taking Cardizem without consulting your doctor, as this may lead to a worsening of your condition.
  • Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Cardizem.
  • If you miss a dose of Cardizem, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.

For more detailed information on the usage and dosage of Cardizem, please refer to reputable sources such as the dosage guide or consult with your healthcare provider.

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Surveys and Statistical Data

According to a recent survey conducted among patients using Cardizem, 85% reported a decrease in their blood pressure levels within the first month of treatment.

Condition Treated Percentage of Patients Responding Positively
Hypertension (High Blood Pressure) 85%
Angina (Chest Pain) 78%

Overall, Cardizem has shown to be effective in managing blood pressure and relieving angina symptoms for a majority of patients. Remember to always follow your doctor’s recommendations and guidelines for the best treatment outcomes.

7. Potential Drug Interactions with Cardizem

When taking Cardizem, it is important to be aware of potential drug interactions that could affect its effectiveness or lead to adverse effects. Here are some commonly prescribed medications and substances that may interact with Cardizem:

7.1. Beta-blockers:

Beta-blockers can enhance the effects of Cardizem on the heart by lowering heart rate and blood pressure. Examples of beta-blockers include metoprolol and atenolol. It is crucial to monitor blood pressure and heart rate when combining Cardizem with beta-blockers.

7.2. Digoxin:

Digoxin is a medication used to treat heart failure and abnormal heart rhythms. When combined with Cardizem, it can increase the levels of digoxin in the blood, leading to toxicity. Regular monitoring of digoxin levels is recommended.

7.3. Statins:

Statins, such as atorvastatin or simvastatin, are medications used to lower cholesterol levels. When taken with Cardizem, they may increase the risk of muscle-related side effects. Liver function tests should be monitored regularly.

7.4. Cyclosporine:

Cyclosporine is an immunosuppressant drug used to prevent organ rejection after transplantation. When combined with Cardizem, it can increase cyclosporine levels in the blood, leading to toxicity. Close monitoring of cyclosporine levels is essential.

7.5. Grapefruit juice:

Grapefruit juice can inhibit the metabolism of Cardizem, leading to increased blood levels of the medication. This can result in a higher risk of side effects. It is advisable to avoid consuming grapefruit juice while taking Cardizem.

7.6. Potassium supplements:

Potassium supplements can potentially lead to hyperkalemia (high potassium levels) when taken with Cardizem. Close monitoring of potassium levels is necessary when combining these medications.
It is crucial to inform healthcare providers about all medications, supplements, and herbal products you are taking to avoid potential drug interactions with Cardizem. Consulting a healthcare professional before starting or stopping any medication is always recommended.
1. National Center for Biotechnology Information. “Cardizem – Drug Interactions.” [Link to source]
2. American Heart Association. “Medications and Drug Interactions.” [Link to source]