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Artridol (Methocarbamol, Indomethacin, Betamethasone)

Active Ingredient: Methocarbamol, Indomethacin, Betamethasone
Dosage: 215 mg/25 mg/0.75 mg
Route of Administration: Oral
Dosage Form: Capsules
Quantity per package: 40

Artridol is an anti-inflammatory drug used to treat acute traumatic processes such as post-traumatic inflammation in tendons, ligaments and joints due to strains and contusions. It also treats soft tissue rheumatism, acute and subacute bursitis, shoulder-hand syndrome, soft tissue inflammation, acute gouty arthritis, osteoarthritis of the peripheral joints and the spine (degenerative rheumatism). Artridol also helps relieve pain.

Artridol is out of stock at the moment but you can order a similar medication for treating inflammation.

Indications

  • Acute cases and exacerbations of patients with rheumatoid arthritis, ankylosing spondylitis, osteoarthritis;
  • Relief of pain and inflammation of acute gouty arthritis, acute and subacute bursitis, tendinitis, synovitis.

Dosage and administration

The drug is taken orally. In severe cases of rheumatoid arthritis and other rheumatic disorders, one capsule is taken every 8 hours for a period of 7 days; the dose should be decreased gradually and weekly, taking one capsule every 12 hours for 7 days; reduce the dose back to one capsule every 24 hours for another week and the fourth week of treatment reduce the dosage until leaving a maintenance dose of one capsule every third day for a week until it is withdrawn, maintaining the appropriate clinical response with a control strict patient without side effects. The doses are variable and can be individualized based on the specific disease, its severity and the patient’s response.

Contraindications

Artridol is contraindicated for use in patients with systemic or infectious fungal infections, in diabetic patients or those with arterial hypertension, in patients with peptic ulcer or renal insufficiency, in patients with a history of hypersensitivity to methocarbamol, betamethasone or salicylates, or any other component of the formula.

Side effects

The adverse reactions of Artridol are the same as those indicated for other corticosteroids and are related to the dosage and duration of treatment. Normally these reactions can be reversed or minimized by decreasing the dosage. If any adverse effects develop, it is usually recommended to stop the treatment. The drug can cause nausea and vomiting, anorexia, epigastric discomfort, abdominal pain, constipation and diarrhea, asthma, rash, blurred vision, headache, dizziness, drowsiness. Prolonged therapy can cause increased blood pressure, weight gain, moon face, hirsutism, acne, hyperglycemia, increased susceptibility to infections, osteoporosis, myopathy, behavioral disorders, cataracts, growth disruption.

Overdose

Overdose can cause nausea, vomiting, severe headache, dizziness, mental confusion, disorientation or lethargy. The treatment is symptomatic and supportive. If the ingestion is recent, the stomach should be emptied as soon as possible. Depending on the patient’s condition, it may be necessary to undergo close medical observation and general care. It may be necessary to administer antacids.

Interaction

Concomitant use of phenobarbital, rifampicin, diphenylhydantoin or ephedrine may increase corticosteroid metabolism by decreasing its therapeutic action. Patients treated concomitantly with a corticosteroid and estrogen should be monitored for the possible increase in corticosteroid effects. The use of other non-steroidal anti-inflammatory drugs concomitantly with Artridol or the use of anticoagulants is not recommended. The simultaneous use with acetylsalicylic acid can potentiate the side effects. Use with probenecid increases the plasma concentration of indomethacin. The antihypertensive effects of thiazide diuretics may be lessened by the presence of indomethacin, as well as adrenergic blockers and angiotensin-converting enzyme inhibitors. Due to the presence of methocarbamol, patients should be advised of the combined effects of using the product with alcohol and other CNS depressants, as well as for the use of vehicles and machinery.