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Cheap Generic Neurontin (Gabapentin) – Useful Information

Table of contents

  1. What is Neurontin?

  2. What is Neurontin used for?
  3. How does Neurontin work?

  4. What is Neurontin dosage?

  5. What are contraindications of Neurontin?
  6. What are the side effects of Neurontin?
  7. What are Neurontin drug interactions?
  8. What are Neurontin withdrawal symptoms?
  9. Gabapentin vs Neurontin
  10. Neurontin pricing
  11. FAQs
  12. Neurontin reviews

What is Neurontin?

Neurontin is a medication that contains the active ingredient gabapentin. It belongs to a class of drugs known as anticonvulsants or antiepileptic drugs. Neurontin is primarily prescribed to treat certain types of seizures and manage neuropathic pain caused by nerve damage or conditions such as shingles, diabetic neuropathy, or fibromyalgia.

This drug comes in various forms, including capsules, tablets, and oral solutions. The medication is typically taken orally, and the dosage and duration of treatment depend on the specific condition being treated, individual response, and other factors as determined by a healthcare professional.

It is available both as a brand-name medication and as a generic version (gabapentin). The generic form may be more affordable, and it has been widely used as a cost-effective alternative to the brand-name Neurontin.

Classification

Neurontin (gabapentin) has several classifications based on its therapeutic use, pharmacological properties, and regulatory status. Here are the main classifications:

  1. Anticonvulsant: It is classified as an anticonvulsant or antiepileptic drug. It is primarily used in the management of epilepsy and to prevent or control seizures.
  2. Analgesic: It is also classified as an analgesic, specifically for the management of neuropathic pain. It is used to help alleviate nerve pain caused by conditions such as diabetic neuropathy, postherpetic neuralgia, and other types of neuropathy.
  3. GABA Analog: It is considered an analog of gamma-aminobutyric acid (GABA), a neurotransmitter that plays a role in inhibiting nerve activity. While Neurontin does not directly bind to GABA receptors, it is believed to enhance the activity of GABA and modulate the release of other neurotransmitters involved in pain signaling.
  4. Prescription Medication: It is available only by prescription. It is classified as a prescription medication due to its potential side effects, interactions, and the need for proper medical supervision and dosing adjustments.

What is Neurontin generic name?

Gabapentin is the generic name for the medication commonly known by the brand name Neurontin. It belongs to the class of drugs called anticonvulsants or antiepileptic drugs. Gabapentin is primarily prescribed for the treatment of epilepsy and neuropathic pain.

As a generic medication, gabapentin is chemically identical to the brand-name Neurontin. Generic medications are typically less expensive than their brand-name counterparts and are approved by regulatory authorities as safe and effective alternatives.

Gabapentin works by binding to a specific subunit of voltage-gated calcium channels in the brain, which helps reduce the release of certain excitatory neurotransmitters involved in the generation of seizures and pain signals. By modulating neurotransmitter activity, gabapentin helps to control seizures and alleviate neuropathic pain.

Gabapentin is available in various dosage forms, including capsules, tablets, and oral solutions. The dosage and frequency of administration are determined based on the individual’s condition, response to treatment, and other factors as determined by a healthcare professional.

What is Neurontin used for?

Neurontin (gabapentin) is prescribed for the treatment of various medical conditions, primarily focusing on epilepsy and neuropathic pain. Here are the main diseases or conditions for which this drug is commonly used:

  1. Epilepsy: it is approved for the treatment of epilepsy. It may be prescribed as an adjunctive therapy to control seizures in individuals with partial seizures or mixed seizures.
  2. Neuropathic Pain: Neurontin is widely used for the management of neuropathic pain. It can be prescribed for conditions such as postherpetic neuralgia (nerve pain that persists after a shingles infection), diabetic neuropathy (nerve damage due to diabetes), peripheral neuropathy (nerve damage in the hands or feet), and other forms of chronic neuropathic pain.
  3. Fibromyalgia: While not officially approved by regulatory authorities for this use, this drug is sometimes prescribed off-label to manage fibromyalgia. It may help alleviate the associated chronic pain and improve sleep disturbances in some individuals.
  4. Restless Leg Syndrome (RLS): It is occasionally used off-label to treat RLS, a condition characterized by uncomfortable sensations in the legs and an irresistible urge to move them. It can help reduce the frequency and intensity of RLS symptoms.
  5. Anxiety Disorders: Neurontin may be prescribed off-label for the management of certain anxiety disorders, such as generalized anxiety disorder (GAD) or social anxiety disorder. It is used as an adjunctive therapy when other first-line treatments have been ineffective or are not suitable.

How does Neurontin work?

The mode of action of Neurontin (gabapentin) involves multiple mechanisms that contribute to its therapeutic effects. Here is a numeric list describing the known modes of action:

  1. Modulation of Calcium Channels: This drug binds to a specific subunit (α2δ-1) of voltage-gated calcium channels in the central nervous system. By binding to this subunit, this medication reduces the influx of calcium ions into nerve cells. This modulation of calcium channels is thought to contribute to the antiepileptic and analgesic properties of Neurontin.
  2. Enhancement of GABAergic Activity: It enhances the activity of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in the brain. It increases the synthesis and release of GABA and enhances GABAergic neurotransmission. By increasing the inhibitory effects of GABA, Neurontin helps to reduce neuronal excitability and stabilize abnormal electrical activity in the brain.
  3. Altered Neurotransmitter Signaling: It may affect the release or actions of other neurotransmitters, such as glutamate, norepinephrine, and substance P. While the exact mechanisms are not fully understood, Neurontin’s modulation of these neurotransmitters may contribute to its analgesic and antiepileptic effects.

How long does it take Neurontin to work?

The onset of action for gabapentin can vary among individuals and depends on various factors, including the condition being treated and the individual’s response to the medication. Here is a general overview of the time it may take for Neurontin to start working:

  1. Epilepsy: When this drug is prescribed for epilepsy, it is often started at a low dose and gradually increased to the target therapeutic dose. The antiepileptic effects of Neurontin may begin to be noticeable within a few days to a few weeks. However, it may take several weeks or even a few months of continuous treatment to achieve optimal seizure control. It’s important to follow the prescribed dosage and allow sufficient time for the medication to take effect.
  2. Neuropathic Pain: For neuropathic pain, the time it takes for this medication to start working can also vary. Some individuals may experience pain relief within a few days of starting treatment, while others may require several weeks or even longer to experience significant improvements. It is common for the dosage to be gradually increased over time to find the most effective and tolerable dose for pain management.
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How long does Neurontin stay in your system?

The half-life of Neurontin (gabapentin) can vary depending on various factors, including individual differences and dosing. The half-life refers to the time it takes for the concentration of a drug in the body to decrease by half. While the reported half-life of Neurontin can range from 5 to 7 hours in adults, it’s important to note that individual variations are possible.

The half-life of this preparation can be affected by factors such as age, liver function, and the presence of other medications. In individuals with impaired kidney function, the elimination may be prolonged, leading to a longer half-life. In such cases, the dosage of Neurontin may need to be adjusted accordingly.

What is Neurontin dosage?

Neurontin (gabapentin) is available in various dosage forms and strengths. The specific dosages prescribed can vary depending on the medical condition being treated and the individual’s needs. Here are some commonly available dosages of Neurontin:

  1. Capsules: available in strengths of 100 mg, 300 mg, and 400 mg.
  2. Tablets: come in strengths of 600 mg and 800 mg.
  3. Oral Solution: available in a concentration of 250 mg/5 mL.

The appropriate dosage of Neurontin varies based on factors such as the condition being treated, the patient’s age, weight, kidney function, and the presence of any other medical conditions. Your healthcare provider will determine the most suitable dosage for you based on these factors.

The maximum and minimum doses can differ depending on the specific condition and individual circumstances. The maximum daily dose for most adults is typically 3600 mg, although some individuals may require higher doses in certain situations. The minimum effective dose varies depending on the condition and individual response, and it is typically determined through a process of starting at a low dose and gradually titrating upwards as needed.

Overdose

An overdose of Neurontin (gabapentin) can occur if someone takes more than the prescribed or recommended dosage. It’s essential to seek immediate medical attention if an overdose is suspected. Here’s some important information:

  1. Symptoms: Overdosing can result in various symptoms, which may vary depending on the individual and the amount of the drug ingested. Common symptoms of an overdose may include drowsiness, sedation, dizziness, blurred vision, slurred speech, loss of coordination, difficulty breathing, increased heart rate, and even seizures in severe cases.
  2. Risk Factors: Certain factors can increase the risk of an overdose, including taking higher-than-prescribed doses, taking it more frequently than recommended, combining this drug with other substances that depress the central nervous system (such as alcohol or sedatives), or having impaired kidney function, as Neurontin is primarily excreted by the kidneys.
  3. Treatment: If an overdose is suspected, immediate medical attention is crucial. The individual may be taken to an emergency room for evaluation and management. Treatment may involve measures to eliminate the drug from the body, such as pumping the stomach (gastric lavage) or administering activated charcoal to absorb the drug. Supportive care, such as monitoring vital signs, providing respiratory support, and treating any complications, will be provided as needed.
  4. Effects and Complications: Severe overdose can lead to serious complications, including respiratory depression (slow or shallow breathing), cardiovascular effects (such as low blood pressure or irregular heartbeat), and even coma. Prompt medical intervention is essential to prevent or manage these complications.
  5. Prevention: To prevent an overdose, it is crucial to strictly adhere to the prescribed dosage and frequency. Never take more gabapentin than prescribed or combine it with other substances without consulting a healthcare professional. If you have concerns about your medication or dosage, speak to your healthcare provider for guidance.

What are contraindications?

Contraindications are specific circumstances or conditions under which a medication like gabapentin should not be used due to the potential risks or lack of effectiveness. Here are examples of common and uncommon contraindications:

  1. Common Contraindications: a. Hypersensitivity: This drug should not be used in individuals with a known hypersensitivity or allergy to gabapentin or any of its components. b. Renal Impairment: Neurontin is primarily eliminated through the kidneys. Therefore, caution is advised and dosage adjustments may be necessary in individuals with impaired renal function.
  2. Uncommon Contraindications: a. Suicidal Ideation: This medication may increase the risk of suicidal thoughts or behavior. Close monitoring and caution are recommended, especially in individuals with a history of depression, suicidal tendencies, or psychiatric disorders. b. Respiratory Depression: Neurontin may cause respiratory depression, particularly when combined with other central nervous system depressants. Therefore, it should be used with caution in individuals with respiratory compromise or compromised lung function. c. Geriatric Population: Neurontin may require dosage adjustments or closer monitoring in elderly individuals due to age-related changes in renal function and other factors.

What are the side effects?

  1. Common Side Effects (may affect 1% to 10% of individuals):
    • Drowsiness or sedation;
    • Dizziness;
    • Fatigue;
    • Nausea or vomiting;
    • Headache;
    • Peripheral edema (swelling of the hands, legs, or feet);
    • Tremors or unsteadiness;
    • Weight gain;
    • Visual disturbances (blurred or double vision).
  2. Often Reported Side Effects (may affect 0.1% to 1% of individuals):
    • Mood changes, including depression or anxiety;
    • Difficulty concentrating;
    • Memory problems or forgetfulness;
    • Coordination problems;
    • Gastrointestinal discomfort or diarrhea;
    • Dry mouth;
    • Increased appetite.
  3. Rare Side Effects (may affect less than 0.1% of individuals):
    • Allergic reactions, such as rash, itching, or hives;
    • Suicidal thoughts or behavior;
    • Severe mood changes or confusion;
    • Respiratory depression (slow or shallow breathing);
    • Liver problems (elevated liver enzymes);
    • Low white blood cell count (leukopenia);
    • Pancreatitis (inflammation of the pancreas).
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What are drug interactions?

Allowed Drug Interactions:

  1. Antacids: Antacids containing aluminum or magnesium hydroxide can be taken with Neurontin, as they do not have significant interactions.
  2. Pain Medications: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or acetaminophen can generally be taken with gabapentin, as there are no known significant interactions.
  3. Antidepressants: Selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and other commonly prescribed antidepressants can often be used in combination with the described drug, but caution is advised due to the potential for additive sedative effects.

Disallowed Drug Interactions:

  1. Opioids: This drug should be used with caution when combined with opioids due to the potential for additive central nervous system (CNS) depressant effects. This combination can increase the risk of respiratory depression and sedation.
  2. Sedatives or Sleep Medications: Combining this pproduct with other sedatives, sleep medications, or tranquilizers can enhance the sedative effects, increasing the risk of excessive drowsiness and impaired coordination.
  3. Alcohol: Drinking alcohol while taking Neurontin is not recommended as it can potentiate the sedative effects of the medication and increase the risk of drowsiness, dizziness, and impaired judgment.
  4. Antacids Containing Calcium: Antacids containing calcium carbonate can potentially reduce the absorption of Neurontin, so it is advisable to separate the administration of these medications by at least two hours.

What are withdrawal symptoms?

Abruptly stopping or rapidly reducing the dose of Neurontin (gabapentin) after long-term use can potentially lead to withdrawal symptoms. Withdrawal symptoms can vary among individuals and may depend on factors such as the duration and dosage of Neurontin use. Here are some commonly reported withdrawal symptoms associated with Neurontin:

  1. Rebound Seizures: This is primarily prescribed for the management of epilepsy and can help prevent seizures. Abruptly stopping Neurontin may increase the risk of rebound seizures, leading to a return or increase in seizure activity.
  2. Anxiety and Restlessness: Some individuals may experience heightened anxiety, restlessness, or irritability upon discontinuation of the drug. These symptoms can be distressing but are usually temporary.
  3. Insomnia or Sleep Disturbances: The withdrawal may cause disruptions in sleep patterns, leading to difficulty falling asleep or staying asleep.
  4. Nausea and Digestive Upset: The withdrawal process can sometimes cause gastrointestinal symptoms such as nausea, vomiting, or abdominal discomfort.
  5. Headaches: Headaches, including migraines, have been reported as withdrawal symptoms after stopping Neurontin.
  6. Flu-like Symptoms: In some cases, individuals may experience flu-like symptoms during Neurontin withdrawal, including fatigue, muscle aches, sweating, and general malaise.

Gabapentin vs Neurontin

Neurontin and gabapentin are the same medication. Neurontin is the brand name for the drug gabapentin. When a pharmaceutical company develops a new medication, they give it a brand name. The active ingredient in Neurontin is gabapentin. Once the patent for the brand-name medication expires, other pharmaceutical companies can produce and sell generic versions of the drug using the generic name, which is gabapentin. Both drugs contain the same active ingredient and have the same effects in the body. The main difference between the two is the brand name and potentially the appearance or packaging of the medication.

Neurontin pricing

Here are some general estimates of the known rates for Neurontin (gabapentin) as of the last knowledge update:

  1. Neurontin Brand Name:
    • Average Wholesale Price (AWP) for Neurontin capsules (300 mg): Approximately $2.50 to $3.00 per capsule.
    • AWP for Neurontin pills (600 mg): Approximately $4.00 to $5.00 per tablet.
    • These prices can vary based on the quantity purchased and the pharmacy or supplier.
  2. Gabapentin (Generic):
    • Generic gabapentin is generally less expensive than the brand-name Neurontin.
    • The average retail price for generic gabapentin (300 mg) can range from $0.50 to $1.50 per capsule.
    • These prices can vary depending on the pharmacy and location.

FAQs

Q: Is neurontin addictive?

A: While Neurontin (gabapentin) is not considered to be highly addictive, it is possible for some individuals to develop a dependence on the medication. The risk of addiction or dependence with Neurontin is generally lower compared to substances classified as controlled substances, such as opioids or benzodiazepines.

Neurontin does not directly activate the brain’s reward system, which is the primary mechanism of action associated with addictive substances. However, it’s worth noting that abrupt discontinuation or rapid dose reduction after prolonged use of this drug can potentially lead to withdrawal symptoms. These withdrawal symptoms can include anxiety, restlessness, insomnia, nausea, and headaches. Therefore, it’s generally recommended to gradually taper off the medication under the guidance of a healthcare professional to minimize the risk of withdrawal symptoms.

Q: Neurontin for dogs – yes or no?

A: Neurontin (gabapentin) is occasionally prescribed for dogs, primarily for the management of chronic pain or as an adjunctive treatment for seizures. However, the use of gabapentin in dogs is considered off-label, meaning it is not FDA-approved specifically for use in dogs.

Veterinarians may prescribe Neurontin for dogs based on their professional judgment and the specific needs of the individual animal. The dosage and frequency of administration for dogs may differ from the recommended human dosage, and it is crucial to follow the veterinarian’s instructions carefully.

Q: Is neurontin a good painkiller?

A: Neurontin (gabapentin) is commonly prescribed as an adjunctive treatment for certain types of chronic pain, including neuropathic pain. While it is not classified as a traditional painkiller, it has shown effectiveness in alleviating pain symptoms in some individuals. Here are some key points regarding Neurontin’s potential as a pain management option:

  1. Adjunctive Pain Relief: Neurontin is often used in combination with other pain management strategies to enhance overall pain relief. It may complement the effects of traditional painkillers and provide additional relief, particularly for neuropathic pain conditions.
  2. Neuropathic Pain Management: Neurontin has been particularly beneficial in managing neuropathic pain, which stems from damage or dysfunction of the nervous system. It can help modulate abnormal nerve activity and reduce pain signals, contributing to improved pain control.
  3. Individual Response: The effectiveness of this drug as a painkiller can vary among individuals. While some people experience significant pain relief, others may have a more modest response or find that alternative pain management approaches are more effective.
  4. Non-Narcotic Option: Unlike opioid-based painkillers, Neurontin is not classified as a narcotic. This can be advantageous for individuals who prefer non-opioid options or are at risk of opioid-related side effects or dependence.
  5. Consideration of Side Effects: Neurontin does have potential side effects, such as drowsiness, dizziness, and gastrointestinal discomfort. Balancing the potential benefits of pain relief against the risk of side effects should be carefully evaluated by both the prescribing healthcare professional and the individual seeking pain relief.
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Q: Does neurontin make you sleepy?

A: Neurontin (gabapentin) has the potential to induce drowsiness and sedation in some individuals. It is not uncommon for Neurontin to cause sleepiness as a side effect.

Q: Neurontin and alcohol – possible combination?

A: The combination of Neurontin (gabapentin) and alcohol should be approached with caution. It is generally advisable to avoid or limit alcohol consumption while applying the therapy. Here are some important points to consider:

  1. Increased Sedation and Central Nervous System (CNS) Depression: Both Neurontin and alcohol can have sedating effects on the central nervous system. Combining the two substances can enhance these effects, potentially leading to excessive sedation, drowsiness, impaired coordination, and cognitive impairment.
  2. Worsened Side Effects: Alcohol can worsen the common side effects of Neurontin, such as dizziness, drowsiness, and difficulty concentrating. This can increase the risk of accidents or injuries.
  3. Impaired Judgment: Both substances can affect cognitive function and impair judgment. Combining them can further compromise decision-making abilities and increase the risk of engaging in risky or dangerous behaviors.
  4. Increased Risk of Overdose: Alcohol can potentiate the effects of Neurontin, potentially increasing the risk of an overdose. It is crucial to use Neurontin only as prescribed and avoid consuming excessive amounts of alcohol.
  5. Individual Variations: The effects of combining both substances can vary among individuals. Factors such as individual sensitivity, dosage of Neurontin, and the amount of alcohol consumed can influence the level of interaction and its impact.

Q: Does neurontin cause weight gain?

A: Neurontin is associated with the possibility of weight gain, although not everyone will experience this side effect. Weight gain can occur due to various factors, such as increased appetite, fluid retention, or metabolic changes.

It’s important to note that weight gain is not a universal side effect of Neurontin, and not everyone taking the medication will experience this effect. Monitoring your weight, maintaining a balanced lifestyle, and working closely with your healthcare provider can help address any weight-related concerns while undergoing this therapy.

Neurontin reviews

Review 1:
Name: Emily
Rating: 5/5

I have been taking Neurontin for my chronic pain, and it has been a lifesaver! The pain relief I’ve experienced is remarkable. I feel like I can finally live a normal life without constant discomfort. It has improved my quality of life tremendously. Highly recommended!

Review 2:
Name: Daniel
Rating: 4/5

Neurontin has been effective in reducing my nerve pain caused by a previous injury. I have noticed a significant decrease in pain intensity and frequency. However, I did experience some mild drowsiness as a side effect. Overall, it has been a beneficial medication for me.

Review 3:
Name: Sophia
Rating: 3/5

I have been using Neurontin for a few weeks to manage my neuropathic pain. While it has provided some relief, the results have been inconsistent. Some days I feel better, while others the pain remains unchanged. I will continue using it, but I’m not sure if it’s the ideal solution for me.

Review 4:
Name: Ethan
Rating: 1/5

Neurontin did not work for me at all. I took it as prescribed for my chronic pain, but it had no noticeable effect. Additionally, I experienced significant dizziness and felt constantly drowsy. I had to discontinue using it due to the side effects. It was a disappointing experience.

Review 5:
Name: Olivia
Rating: 4/5

Neurontin has been helpful in managing my fibromyalgia pain. It has reduced the intensity of my pain and improved my overall well-being. However, I did experience some initial drowsiness, which gradually subsided over time. Despite this, I’m grateful for the relief it has provided.

Review 6:
Name: Benjamin
Rating: 3/5

I’ve been taking Neurontin for my nerve pain, and while it has provided some relief, I haven’t noticed a significant improvement. The pain is still present, but at a more manageable level. I haven’t experienced any side effects, which is a positive aspect. It’s an average medication for me.

Review 7:
Name: Ava
Rating: 2/5

Unfortunately, Neurontin didn’t work for my chronic pain. I didn’t experience any noticeable relief, and it caused me to feel extremely fatigued and foggy. It was difficult to function while taking it. I had to discontinue using it due to the lack of effectiveness and undesirable side effects.

Review 8:
Name: Jacob
Rating: 5/5

Neurontin has been a game-changer for my neuropathic pain. The reduction in pain has been remarkable, and I can finally engage in activities I couldn’t before. I haven’t experienced any side effects, which is a huge plus. I highly recommend Neurontin to anyone struggling with nerve pain.

Review 9:
Name: Lily
Rating: 3/5

Neurontin has provided moderate pain relief for my sciatica. While it hasn’t completely eliminated the pain, it has made it more manageable. However, I did experience some dizziness and sleep disturbances as side effects. It’s helpful to some extent, but I’m still searching for better options.

Disclaimer: The information provided on this page is intended for informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read in this instruction for use. The information provided on this page not be applicable to you, as every individual’s medical history and circumstances are unique. Use of any information provided on this page is solely at your own risk. The manufacturer of this medicine is not responsible for any damages or adverse consequences resulting from the use of this medication without the guidance and supervision of a licensed healthcare provider.