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Dislep (Levosulpiride)

Active Ingredient: Levosulpiride
Dosage: 25 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 20
Availability: Out of stock

Dislep is a selective antagonist of the dopamine D2 receptor. It affects both central and peripheral levels. It belongs to atypical neuroleptic and prokinetic agents. Levosulpiride, the main drug components, is also claimed to have mood-elevating properties. Currently, Dislep is unavailable. Surf the mental health category to find another product with the same properties.


  • Dyspeptic syndrome (anorexia, meteorism, the sensation of epigastric tension, heartburn, belching, constipation, vomiting, nausea, etc.);
  • Delayed gastric depletion connected to organic factors (diabetic gastroparesis, neoplasia, etc.);
  • Functional (visceral somatizations).

Dosage and administration

Dose regimen: 1 tablet 3 times a day before meals. In the treatment of elderly patients, the dosage should be defined by the doctor who should evaluate a reduction of the indicated doses.


Dislep is contraindicated in patients with pheochromocytoma because it can cause a hypertensive crisis, probably due to the release of catecholamines by the tumor. Such hypertensive crises can be controlled with phentolamine.

Dislep is contraindicated in patients with known hypersensitivity or drug intolerance.

It should not be used in epilepsy, in manic states or in manic crises of manic-depressive psychosis.

Because of the possible correlation between the hyperprolactinemic effect of most psychotropic drugs and breast dysplasia, it is not appropriate to use Dislep in subjects who already transfer a malignant mastopathy.

Side effects

In prolonged administration, in some cases, disorders such as amenorrhea, gynecomastia, galactorrhea, and alterations of the libido may appear due to the action of levosulpiride on the functionality of the hypothalamic-pituitary-gonad axis. These effects are reversible. If undesirable effects other than those described are found, inform your doctor.

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An overdose could transfer into extrapyramidal disorders and sleep disturbances. If this occurs, adequate palliative symptomatic treatment should be prescribed.


  • The combined therapy with psychoactive drugs requires special caution from the physician to avoid undesirable effects unforeseen by interactions.
  • The effects of levosulpiride on gastrointestinal motility can be antagonized by anticholinergic, narcotic and analgesic drugs.