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Espaven M.D. (Metoclopramide, Dimethicone)
Active Ingredient: Metoclopramide, Dimethicone
Dosage: 40 mg/10 mg
Route of Administration: Oral
Dosage Form: Capsules
Quantity per package: 20 capsules per pack
Why is Espaven M.D. not used in the USA?
Espaven M.D. is not commonly used in the USA, possibly due to regulatory factors and the availability of alternative medications that are preferred under American healthcare protocols. Additionally, the U.S. has stringent approval processes for drugs, and combination drugs like Espaven M.D. may not have sought or received approval from the FDA.
Similar Espaven M.D. Drugs in the USA
In the USA, there are several medications available that can be used to treat the same symptoms as Espaven M.D., particularly for preventing nausea and vomiting associated with medical treatments:
Antiemetics (for nausea and vomiting prevention):
Used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery.
$0,70 per pill
Increases muscle contractions in the upper digestive tract, speeding up the rate at which the stomach empties into the intestines and helps prevent nausea and vomiting.
$0,56 per pill
What is Espaven M.D.?
Espaven M.D. is a combination of metoclopramide and dimethicone. It is used to prevent postoperative nausea and vomiting, induced by radiotherapy or delayed chemotherapy-induced. It is also used to treat nausea and vomiting including those induced by acute migraine; in children and adolescents.
Indications
- Gastroesophageal reflux with or without delay of gastric emptying, gastric hypotonia;
- Postprandial fullness, nausea and vomiting, hiatal hernia, diabetic and post-surgical gastroparesis;
- Emesis prophylaxis induced by chemotherapy.
Dosage and administration
Take one capsule orally, 30 minutes before each meal or before bedtime.
Popularity and Usage in Specific Countries
Espaven M.D. is popular in countries such as Mexico and other parts of Central America, where there is a high acceptance and usage of combination drugs for gastrointestinal and postoperative care. It’s often used in these regions due to its effectiveness in treating multiple symptoms with a single formulation, which can simplify treatment regimens.
Contraindications
- Hypersensitivity to the components of the formula;
- Mechanical obstruction or gastrointestinal perforation;
- Duodenal ulcer;
- Bleeding from the digestive tract;
- Pheochromocytoma;
- Seizure disorders.
Espaven M.D. is also contraindicated as a prophylactic antiemetic in patients with breast cancer under chemotherapy.
Side effects
In rare cases, Espaven M.D. can cause the following adverse reactions: vertigo, asthenia, insomnia, headache, dysphoria, dyskinesias, diarrhea, dry mouth and hypersensitivity reactions, galactorrhea.
Overdose
Doses up to 1 g / day have been administered without toxic effects. Overdose of Espaven M.D. can cause vertigo, ataxia, agitation, hyperexcitability, extrapyramidal reactions, oculogyric seizures and seizures. Treatment: gastric lavage and supportive care, or central action anticholinergics. Symptoms of overdose disappear within 24 hours.
Interaction
Espaven M.D. can delay the absorption of paracetamol, acetylsalicylic acid, diazepam, levodopa, lithium and tetracyclines. It potentializes CNS depressant barbiturates, anesthetics and alcohol. It antagonizes anticholinergics. It can increase the appearance of extrapyramidal reactions if it is associated with butyrophenone and phenothiazines.