Table of Contents:
- What is Sildalis?
- How it works
- Indications for use
- Dosage & how to use
- Potential side effects
- Drug interactions
- Sildalis vs Viagra vs Cialis
- Frequently Asked Questions
Sildalis is a generic medication used to treat erectile dysfunction (ED) in men. It contains a combination of sildenafil citrate and tadalafil, which work together to improve blood flow to the penis and enhance sexual performance. The drug provides a longer-lasting and more potent effect than either drug alone, making it a popular treatment option for men experiencing ED. However, it is important to note that the tablet does not increase sexual desire or libido and will not cure ED. Before using these pills, it is crucial to speak with a healthcare provider to ensure it is safe and appropriate for your individual needs. With its unique combination of active ingredients, the drug has helped many men regain their sexual confidence and improve their overall sexual health.
It is a combination of two active ingredients, sildenafil citrate and tadalafil, both of which work to increase blood flow to the penis and enable an erection during sexual stimulation. In this article, we will delve into the mechanism of action of Sildalis 120mg and explore how it works to treat ED.
Sildenafil citrate and tadalafil are both phosphodiesterase type 5 (PDE5) inhibitors. PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a chemical messenger that helps to relax the smooth muscles in the penis and increase blood flow during sexual stimulation.
In men with ED, PDE5 breaks down cGMP too quickly, which results in inadequate blood flow to the penis, making it difficult to achieve and maintain an erection. Sildenafil and tadalafil work by inhibiting PDE5, allowing cGMP to accumulate and improve blood flow to the penis, resulting in a sustained erection during sexual activity.
Sildenafil citrate is the active ingredient in Viagra, while tadalafil is the active ingredient in Cialis. Sildalis 120 mg is unique in that it combines the benefits of both drugs to provide a more potent and longer-lasting effect than either drug alone.
When a man is sexually stimulated, the brain releases nitric oxide (NO), which triggers the production of cGMP. cGMP causes the smooth muscles in the penis to relax, allowing blood vessels to dilate and increase blood flow to the penis, leading to an erection.
This medicine works by enhancing the effects of NO and cGMP, allowing the smooth muscles in the penis to relax and the blood vessels to dilate, leading to improved blood flow to the penis and facilitating an erection during sexual activity. The pill is effective for up to 36 hours after ingestion, making it a popular choice for men seeking a more prolonged and effective treatment for ED.
- Men with Erectile Dysfunction: The drug is primarily used by men who have difficulty achieving or maintaining an erection sufficient for sexual activity. ED can be caused by physical, psychological, or lifestyle factors, and the medicine is effective in treating ED regardless of the cause.
- Men with Pulmonary Arterial Hypertension: It may also be used by men with pulmonary arterial hypertension (PAH), a condition where the blood pressure in the arteries that carry blood from the heart to the lungs is too high. Sildenafil citrate, one of the active ingredients in the drug, can help to relax the walls of these blood vessels and lower blood pressure.
- Men with Raynaud’s Disease: The product may be used by men with Raynaud’s disease, a condition where the blood vessels in the fingers and toes constrict and narrow, causing pain and numbness. Tadalafil, one of the active ingredients in Sildalis, can help to relax these blood vessels and improve blood flow.
- Men with Benign Prostatic Hyperplasia: It may also be used by men with benign prostatic hyperplasia (BPH), a condition where the prostate gland becomes enlarged and can cause urinary problems. Tadalafil, one of the active ingredients in the drug, can help to relax the muscles in the prostate and bladder and improve urinary symptoms.
- Men who have Tried Other ED Medications Without Success: The pills may be used by men who have tried other ED medications without success. The combination of sildenafil citrate and tadalafil may provide a more effective treatment option for these individuals.
- Sildalis is typically taken orally, 30 minutes to an hour before sexual activity.
- The recommended dosage is usually 100mg of sildenafil citrate and 20mg of tadalafil.
- The pill should be taken with a full glass of water.
- The maximum recommended dosage is 120mg of sildenafil citrate and 20mg of tadalafil per day.
- Do not exceed the maximum recommended dosage, as it can increase the risk of side effects.
- The pill should not be taken more than once a day.
- It can be taken with or without food, but it is recommended to avoid a high-fat meal before taking the medication.
- Grapefruit or grapefruit juice should be avoided while taking this medicine, as it can increase the concentration of the medication in the blood and lead to an increased risk of side effects.
- Dosage adjustments may be necessary for elderly patients or those with kidney or liver impairment.
- It is important to consult with your healthcare provider before taking these pills to determine the appropriate dosage for your individual needs and medical history.
Here’s a table listing potential Sildalis side effects based on their frequency of occurrence:
|Frequency of Occurrence||Side Effect|
|Sudden hearing loss|
|Sudden vision loss|
|Nausea and vomiting|
|Unfrequent||Abnormal liver function|
|Low blood pressure|
|High blood pressure|
|Increased heart rate|
|Very Rare||Blood in urine or stool|
|Muscle weakness or pain|
It’s important to note that while these are some of the potential side effects associated with this medicine, not everyone who takes the medication will experience them.
Additionally, the frequency of occurrence of each side effect can vary depending on factors such as age, health status, and dosage. If you have any concerns or questions about the potential side effects of your drug, speak with your healthcare provider. They can help you understand the risks and benefits of the medication and determine if it is right for you.
Here is a list of potential drug interactions with Sildalis (sildenafil 100mg tadalafil 20mg) categorized by their level of interaction:
Possible drug interactions:
- Antibiotics: Erythromycin, Clarithromycin, Azithromycin
- Antifungal medications: Ketoconazole, Itraconazole
- HIV medications: Ritonavir, Saquinavir
- Grapefruit juice
- Protease inhibitors: Indinavir, Nelfinavir, Ritonavir
- Antidepressants: Fluoxetine, Paroxetine, Sertraline
- Certain antibiotics: Rifampin, Rifabutin
- Anticonvulsants: Carbamazepine, Phenytoin
- Antipsychotic medications: Haloperidol, Chlorpromazine
- Other medications for erectile dysfunction: Tadalafil, Sildenafil
- PDE-5 inhibitors: Avanafil, Vardenafil
Safe drug interactions:
- Blood pressure medications: Amlodipine, Diltiazem, Verapamil
- Antihypertensive medications: Enalapril, Lisinopril, Hydrochlorothiazide
Contraindicated drug interactions:
- Nitrates: Nitroglycerin, Isosorbide dinitrate, Isosorbide mononitrate
- Alpha-blockers: Tamsulosin, Terazosin, Doxazosin
- Other medications for pulmonary arterial hypertension (PAH): Riociguat
- Nitric oxide donors: Amyl nitrate, Nitroglycerin
- Certain medications for heart conditions: Atenolol, Metoprolol, Nitroglycerin
It is important to note that this is not an exhaustive list of potential drug interactions with Sildalis 120mg. Always inform your healthcare provider of all medications and supplements you are taking before starting these pills. They can help you determine if there are any potential drug interactions and if this medicine is safe for you to take.
Here are some precautions to keep in mind when using Sildalis 100mg + 20mg:
- Use caution when taking this drug if you have a history of kidney or liver disease, as these conditions can affect how your body processes the medication.
- If you are taking medication for high blood pressure, talk to your healthcare provider before taking these pills, as it can cause a drop in blood pressure.
- Avoid taking these pills with high-fat meals, as this can delay the onset of action and reduce its effectiveness.
- If you experience chest pain, nausea, or other symptoms of a heart attack while taking this medication, seek medical attention immediately.
- Use caution when taking this drug if you have a history of bleeding disorders or stomach ulcers.
- If you experience an allergic reaction to sildenafil or tadalafil, stop taking the medication and seek medical attention immediately.
- Do not take this drug if you are already taking medication for erectile dysfunction or pulmonary arterial hypertension.
- If you are over the age of 65, use caution when taking these pills, as you may be more sensitive to its effects.
- Women should not take this drug, as it is intended for use in men only.
- Keep the medicine out of reach of children and pets.
By following these precautions and using these pills as directed by your healthcare provider, you can help reduce your risk of side effects and ensure the medication is safe and effective for you. If you have any concerns or questions about using this medicine, talk to your healthcare provider.
These are all medications used to treat erectile dysfunction in men. While they work in similar ways to improve blood flow to the penis and help achieve and maintain erections, there are some differences between them. Here are some potential differences between Sildalis, Viagra, and Cialis:
- Active ingredients: Sildalis contains both sildenafil and tadalafil, while Viagra contains only sildenafil and Cialis contains only tadalafil.
- Onset of action: Sildalis and Viagra typically start working within 30-60 minutes, while Cialis can take up to 2 hours to take effect.
- Duration of action: Sildalis can last up to 36 hours, Cialis can last up to 36 hours, and Viagra typically lasts 4-6 hours.
- Flexibility in timing sexual activity: Sildalis and Cialis provide more flexibility in timing sexual activity due to their longer duration of action, while Viagra requires more precise timing.
- Side effects: All three medications may cause potential side effects, but the specific side effects and their severity may vary.
- Dosage: Sildalis is typically available in a 120mg dose, while Viagra and Cialis come in various doses (25mg, 50mg, and 100mg for Viagra and 2.5mg, 5mg, 10mg, and 20mg for Cialis).
- Cost: The cost of these medications may vary depending on factors such as the dose, the pharmacy, and insurance coverage.
- Safety: All three medications are generally considered safe when used as directed and under the supervision of a healthcare provider. However, they may interact with certain medications and may not be safe for men with certain medical conditions.
- Effectiveness: The effectiveness of these medications may vary from person to person, and some men may find that one medication works better for them than another.
It is important to talk to a healthcare provider to determine which medication is the best option for you based on your specific needs and medical history.
Q: How should Sildalis be stored?
A: The drug should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children.
Q: How long does Sildalis last?
A: It usually lasts an average of 4-6 hours. However, the duration may be longer for some individuals depending on their metabolism and other factors. It is important to follow the dosage instructions provided by a healthcare professional and not take more than one dose in a 24-hour period.
Q: How often can I take Sildalis?
A: It should be taken as directed by a healthcare provider. Do not take more than one dose of Sildigra in a 24-hour period.
Q: Can the pill be taken with food?
A: It can be taken with or without food. However, a high-fat meal may delay the onset of action.
Q: How long can you keep Sildalis 120 mg?
A: The shelf life of this drug varies depending on factors such as storage conditions and the manufacturing date. Typically, it has a shelf life of around 2-3 years. However, it is always important to check the expiration date before using Sildalis 100mg + 20mg or any other medication and to discard any expired medication. Proper storage, such as keeping it in a cool, dry place away from direct sunlight, can help extend the shelf life of the medicine.
Q: Can I buy cheap Sildalis 120mg?
A: It is possible to buy sildalis 120 mg at a discount, but it is important to be cautious when purchasing it. To ensure safety and quality, it is recommended to only buy Sildalis from licensed and reputable sources, whether online or offline. Additionally, it is important to consult with a healthcare professional before taking medication for erectile dysfunction.
Q: Can this drug be taken by women?
A: It is not intended for use by women and should only be used by men who have been diagnosed with erectile dysfunction.
Q: Is it safe to take with alcohol?
A: It is not recommended to take ED medicine with alcohol, as this may increase the risk of side effects and decrease the effectiveness of the medication.
Q: How long does it take for Sildalis to start working?
A: It typically starts working within 30-60 minutes after taking the medication.
Q: Can this drug be taken with nitrate medications?
A: It should not be taken with nitrate medications, as this may cause a dangerous drop in blood pressure.
Q: Can it be taken by men with diabetes?
A: Men with diabetes may be able to use the drug, although it is important to discuss this with a healthcare provider to ensure safety and effectiveness.
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Disclaimer: The information provided on this page is intended for informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read in this instruction for use. The information provided on this page not be applicable to you, as every individual’s medical history and circumstances are unique. Use of any information provided on this page is solely at your own risk. The manufacturer of this medicine is not responsible for any damages or adverse consequences resulting from the use of this medication without the guidance and supervision of a licensed healthcare provider.