Novaxen (Naproxen)

Active Ingredient: Naproxen
Dosage: 250 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 30 tablets per pack

Novaxen (naproxen) is a nonsteroidal anti-inflammatory drug that can treat fever and pain. It is used in the treatment of headache, muscle aches, tendonitis, dental pain, and menstrual cramps, arthritis, bursitis, and gout attacks. Currently, this drug is unavailable. Search for another treatment option here.

Indications

Novaxen is an anti-inflammatory drug with analgesic action. It provides anti-inflammatory-analgesic action in the postoperative period of tonsillectomies and oropharyngeal surgery, dental procedures, trauma, rheumatoid arthritis, and osteoarthritis.

Dosage and administration

Dosage in adolescents and adults (tablets): 2 tablets (500 mg) twice a day or a single dose of 1,000 mg daily.

Novaxen should be taken with food or antacids. It suppresses the intake of alcoholic beverages during treatment.

Contraindications

The most common of Novaxen are:

hypersensitivity to other medications containing naproxen;
history of an asthmatic syndrome, rhinitis, and urticaria caused by acetylsalicylic acid or other non-steroidal analgesics.

Novaxen is contraindicated in patients who have had allergic reactions to naproxen or sodium naproxen. It is also contraindicated in patients in whom acetylsalicylic acid (ASA) or other nonsteroidal analgesic/anti-inflammatory drugs have induced asthma, rhinitis or nasal polyps. Both types of reactions have considered being fatal.

Anaphylactic reactions to Novaxen usually, but do not always, occur in patients with a clinical history of such reactions.

If any of these symptoms occur during treatment, the medication should be discontinued.

Naproxen is contraindicated in patients with an active peptic ulcer.

Side effects

The most common side effects are:

gastrointestinal system: constipation, heartburn, abdominal pain, nausea, dyspepsia, diarrhea, and stomatitis.
central nervous system: headache, confusion, drowsiness, dizziness, vertigo.
dermatological: pruritus, skin rashes, ecchymosis, sweating, purple.
sense organs: hearing and visual disturbances, tinnitus.
cardiovascular system: edema, dyspnea, palpitations.
general: thirst.

Side effects met less than in 1% are:

gastrointestinal system: abnormal liver function tests, gastrointestinal bleeding and/or perforation, hematemesis, jaundice, peptic ulceration with bleeding and/or perforation.
renal: glomerular nephritis, hematuria, interstitial nephritis, nephrotic syndrome, and kidney disease.
hematologic: agranulocytosis, eosinophilia, granulocytopenia, leukopenia, thrombocytopenia.
central nervous system: depression, sleep abnormalities, inability to concentrate, insomnia, myalgia and muscle weakness.
dermatological: alopecia, photosensitivity dermatitis, urticaria.
organs of the senses: decreased hearing ability.
cardiovascular: congestive heart failure.
respiratory: eosinophilic pneumonitis.
general: anaphylactic reactions, menstrual abnormalities, hyperpyrexia.

Overdose

Significant overdose can be characterized by drowsiness, heartburn, indigestion, nausea or vomiting. In cases of accidental or provoked overdose, vomiting should be induced and the necessary support measures established. It is administered 10 g of activated carbon to reduce the absorption of naproxen. Hemodialysis may be useful in patients with renal impairment.

Interaction

Novaxen should not be administered in combination with antihypertensive drugs from a group of beta-blockers of the propanolol type.

The simultaneous administration of acetylsalicylic acid decreases the half-life of naproxen; together with oral anticoagulants the anticoagulant effect is increased, the toxicity to these anticonvulsants is increased.

Naproxen with sulfonamides increases the toxicity of these drugs. Its association with sulfonylureas increases hypoglycemia. The natriuretic effect of furosemide has been inhibited by some medications of the same class as naproxen.