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Oxigricol Infantil (Loratadine, Paracetamol, Ascorbic Acid)

Active Ingredient: Loratadine, Paracetamol, Ascorbic Acid
Dosage: –
Route of Administration: Intravenous
Dosage Form: Solution
Quantity per package: 2 ampoules

Oxigricol injection is indicated as antihistamine, decongestant, analgesic, antipyretic. It’s used for the symptomatic management of fever, malaise, headache, nasal congestion, runny and nasal itching, lacrimation present in rhinitis and hay fever in children.

Oxigricol Infantil is currently out of stock but you can explore other options for treating symptoms of a cold.

Indications

Oxigricol Infantil is effective in rickettsias, spotted rocky mountain fever, typhoid, typhic fevers, tick fever. The drug is used to treat infections caused by mycoplasma pneumoniae, Chlamydia trachomatis (venereal granuloma), Calymmatobacterium donovani (inguinal granuloma agent), spirochete of recurrent fever, Neisseria gonorrhoeae, Haemophilus ducreyi (chancroid), Yersinia pestis, Pasteurella tularensis, Bacteroides Vibrio cholerae, Campylobacter fetus, Enterobacter aerogenes. It is indicated in the treatment of respiratory, dermatological, gynecological, urinary tract infections, in post-surgery, brucellosis, etc.

Dosage and administration

Use as directed by a doctor. Never exceed the recommended dose.

Contraindications

Oxigricol Infantil is contraindicated for use in patients with hypersensitivity, kidney or liver disease.

Side effects

Various degrees of gastrointestinal irritation may occur, a patient may experience burning, epigastric and abdominal discomfort, nausea, vomiting, so it is suggested that in these cases the drug is administered with food (not milk, dairy or antacids). In some cases, diarrhea, pigmentation of the nails, liver toxicity, kidney damage, pigmentation of the teeth may occur, so the drug should not be administered in pregnant or nursing women, as it crosses the placental barrier and can cause the mentioned pigmentation.

Overdose

The effects of an Oxigricol overdose can range from CNS depression (sedation, apnea, decreased alertness, cardiovascular collapse) to stimulation (insomnia, hallucinations, tremors or convulsions) to death. There may be dizziness, tinnitus, ataxia, blurred vision and hypotension.

The symptoms of paracetamol overdose are paleness and may include nausea, vomiting, anorexia, gastrointestinal bleeding, liver damage, cerebral edema and renal tubular necrosis. A serious complication is acute liver necrosis. Symptoms may not appear immediately. Patients who have ingested an excessive dose of paracetamol cannot look apparently good during the three days following the ingestion of excessive doses and then suffer from liver disease. After a dose of paracetamol, cases of hyperglycemia and hypoglycemia have been reported.

Treatment: Vomiting should be induced in the patient even if spontaneous emesis has occurred. Vomiting produced pharmacologically by the administration of syrup of ipecac is preferred. However, vomiting should not occur in patients with impaired consciousness. If emesis does not occur within 15 minutes, gastric lavage should be done. The solutions for gastric lavage are isotonic and isotonic saline media. Saline cathartics attract water to the intestines by osmosis and therefore can be valuable for their action to rapidly dilute the intestinal contents. With an overdose by acetaminophen, gastric lavage should be followed by N-acetylcysteine ​​intravenously or methionine orally. Acidosis and loss of electrolytes must be corrected. Vasopressor agents can be used to treat hypotension. To control seizures, short-acting barbiturates such as diazepam or paraldehyde can be administered.

Interaction

The concomitant use of antihistamine, tricyclic antidepressants, barbiturates and other CNS depressants may potentiate the sedative effect of loratadine. Paracetamol can increase the activity of coumarin anticoagulants. Enzyme inducing medications such as barbiturates and alcohol can accelerate paracetamol metabolism and increase the risk of developing liver necrosis associated with paracetamol overdose.