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Avapena (Chloropyramine)

Active Ingredient: Chloropyramine
Dosage: 25 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 20
Availability: Out of stock

Why is Avapena not used in the USA?

Avapena is not used in the USA primarily because newer generation antihistamines, which have fewer sedative effects and longer durations of action, are preferred. The US market favors antihistamines such as Cetirizine, Loratadine, and Fexofenadine, which provide effective relief with fewer side effects like drowsiness.

What are the equivalent drugs of Avapena available in the USA?

Here are some drugs available in the USA that are used to treat the same diseases and symptoms as Avapena:

Managing Allergy Symptoms:

Allergy symptoms can include nasal congestion, runny nose, itchy or watery eyes, sneezing, hives, or skin rash. Here are medications effective in coping with these symptoms:

Medications for Asthma Treatment and Relief:

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What is Avapena?

Avapena is a first-generation antihistamine drug, which is used to treat allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Chloropyramine works by blocking histamine receptors in the body, which helps reduce symptoms associated with allergic reactions such as itching, swelling, and rashes.


Avapena is typically available in tablet form, injections, and sometimes as a topical cream. The usual oral dosage for adults is 25 mg three to four times a day. For children, the dosage must be reduced and tailored to their age and weight. Injections may be used for more severe reactions and are usually administered by a healthcare professional.

Popularity and Use in Specific Countries

Avapena is popular in countries where newer generation antihistamines are less accessible or more expensive. It is commonly used in parts of Eastern Europe, Latin America, and some Asian countries. The popularity in these regions can also be attributed to its effectiveness in treating a wide range of allergic symptoms, which are prevalent due to environmental factors such as pollution and high pollen counts.