Biodexan Ofteno (Dexamethasone, Neomycin, Polymyxin B, Phenylephrine)

Active Ingredient: Dexamethasone, Neomycin, Polymyxin B, Phenylephrine
Dosage: 5 ml
Route of Administration: Ocular
Dosage Form: Solution
Quantity per package: 1 unit
Availability: Out of stock

Biodexan Ofteno is a combination of dexamethasone with neomycin and polymyxin B. The drug is used to treat eye conditions caused by bacterial infections.

This product is no longer available but you can find a worthy alternative to Biodexan Ofteno on this page.

Indications

The combination of dexamethasone with neomycin and polymyxin B is indicated in the inflammatory eye conditions for which a steroid is indicated and there is also a bacterial infection by microorganisms susceptible to neomycin or polymyxin B. The addition of phenylephrine to this combination decreases the conjunctival hyperemia caused by vasodilation.

Indicated as postoperative prophylaxis of eye surgery.

Dosage and administration

Apply 1 to 2 drops of Biodexan Ofteno to the bottom of the lower conjunctival sac of the affected eye (s) every 4 to 6 hours, according to the intensity of the condition.

In complicated cases or with severe postoperative inflammation, it is recommended to start with applications every 2 hours, then reduce the frequency of applications as the inflammation decreases and monitor the intraocular pressure.

Contraindications

Do not use this medicine if you have any of the following conditions:

• hypersensitivity to the components of the formula;
• epithelial keratitis due to Herpes simplex (dendritic keratitis);
• ocular tuberculosis;
• fungal conditions of the eyeball;
• viral keratoconjunctivitis due to chickenpox virus, vaccine virus, rubella virus and others;
• infections by microorganisms resistant to neomycin or polymyxin B;
• narrow chamber angle.

The drug should be used with caution in patients with systemic arterial hypertension and those heart diseases that are affected by a-adrenergic agents.

Side effects

Biodexan Ofteno can cause the following adverse reactions: increased intraocular pressure with possible appearance of glaucoma, formation of posterior subcapsular cataract, secondary ocular infections by fungi or viruses released from the ocular tissues, delayed wound healing and perforation of the eyeball when the cornea or sclera are thinned, transient irritation, stitched epithelial erosions of the cornea and allergic blepharoconjunctivitis, mydriasis in sensitive patients, hypertension, cardiac arrhythmias, headache, tremor and sweating.

Prolonged use of these eye drops can lead to exaggerated growth of non-susceptible organisms.

Overdose

Overdosing may cause side effects. In case of overdose, administer oral fluids to dilute the product and consult your doctor.

Interaction

Avoid using these eye drops together with bacteriostatic agents (chloramphenicol, sulfonamides, tetracycline, erythromycin, nitrofurazone).

Steroids decrease the action of antibiotics, which can be avoided by increasing the dose of antibiotics.