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Dimegan D (Loratadine, Phenylephrine)

Active Ingredient: Loratadine, Phenylephrine
Dosage: 60 ml
Route of Administration: Oral
Dosage Form: Syrup
Quantity per package: 1
Availability: Out of stock

Dimegan D is prescribed for the treatment of allergy symptoms. It is released in the form of syrup.

Dimegan D is currently out of stock but you can purchase alternatives to treat allergy here.

Indications

The drug is indicated in the symptomatic treatment of allergic rhinitis, nasal congestion and nasal eye pruritus.

Dosage and administration

The syrop is taken orally. Children 6 to 12 years of age: ½ teaspoon (2.5 ml) every 12 hours. Adults and Children over 12 years of age: One 5 ml teaspoon every 12 hours.

Contraindications

  • Hypersensitivity to the components of the formula;
  • Treatment with MAO inhibitors;
  • Narrow-angle glaucoma;
  • Urinary retention;
  • Severe hypertension;
  • Severe coronary artery disease and hyperthyroidism;
  • Peptic ulcer;
  • Stenosonant;
  • Diabetes mellitus.

Side effects

When used at therapeutic doses, Dimegan D is well tolerated, however, some patients may experience severe hypertension, headache, vomiting and reflex bradycardia, fatigue, headache, drowsiness, dry mouth, nausea, gastritis, rash, insomnia and rarely alopecia, anaphylaxis or liver disorders with the use of loratadine. Elderly patients are more susceptible to the hypertensive and bradycardial effects of phenylephrine, so they may have reduced cardiac output as a result of sinus bradycardia, increasing the risk of possible heart failure.

Overdose

In case of overdose, general symptomatic treatment should be started immediately. Patients who took excessive doses of Dimegan D experienced tachycardia, headache and drowsiness. Hemodialysis is not effective.

Interaction

Concomitant use with ketoconazole, erythromycin and cimetidine may cause an increase in loratadine concentrations. Beta-blockers can increase the vasoconstrictor effects of phenylephrine. MAO inhibitors can prolong and intensify the pressor effects of phenylephrine as well as oxytocin.