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Dolprofen (Ibuprofen)

Active Ingredient: Ibuprofen
Dosage: 600 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 10 tablets per pack
Availability: Out of Stock

Why Is Dolprofen Not Used in the USA?

Dolprofen, which contains Ibuprofen, isn’t sold in the USA primarily because of the highly competitive nature of the American pharmaceutical market. Established brands like Advil and Motrin already dominate the sector, offering well-trusted options for Ibuprofen-based medications. Additionally, introducing a new brand like Dolprofen requires FDA approval, which involves rigorous scrutiny of the drug’s safety and efficacy. The presence of similar, well-established products can make it economically unfeasible for new brands to invest heavily in the necessary marketing and distribution networks.

Furthermore, if Dolprofen features any unique formulation or dosing that differentiates it from existing Ibuprofen products, it would need specific regulatory endorsements from the FDA. This regulatory requirement, combined with substantial marketing and logistical challenges, limits the introduction of new pharmaceutical brands like Dolprofen in a market that already has multiple similar offerings.

Drugs Used in the USA for Similar Conditions

Here are drugs sold in the USA that contain Ibuprofen or are used to treat similar symptoms of pain, fever, and inflammation:

See also  Cartigen (Diacerein)

What is Dolprofen?

Dolprofen is a non-steroidal anti-inflammatory drug that is commonly used for the management of mild to moderate pain, fever, and inflammation caused by painful menstrual periods, migraines, and rheumatoid arthritis. The drug usually begins working within 1 hour.

Indications

Dolprofen (ibuprofen) is indicated for the relief of mild to moderate pain, including headaches, toothaches, menstrual cramps, muscle aches, and arthritis. It is also used to reduce fever and inflammation associated with various conditions such as rheumatoid arthritis, osteoarthritis, and juvenile idiopathic arthritis.

Popularity and Use of Dolprofen in Specific Countries

Dolprofen is popular in many countries worldwide due to its effectiveness, affordability, and over-the-counter availability. It’s commonly used in both developed and developing regions.

  • Latin America: In countries like Mexico, Brazil, and Argentina, Ibuprofen is widely used due to its effectiveness and over-the-counter availability. It’s commonly found under various brand names and generics. In these regions, the accessibility of Ibuprofen at pharmacies without a prescription makes it a popular choice for managing pain, fever, and inflammation.
  • Europe: Ibuprofen is one of the most commonly used NSAIDs across European countries, including the UK, Germany, France, and Spain. It is valued for its dual action of reducing pain and inflammation and is readily available over the counter in most places, making it a staple in home medicine cabinets.
  • Asia: In countries like India, China, and Japan, Ibuprofen is popular for its affordability and efficacy. It’s used to treat a variety of conditions from simple headaches and fevers to more complex inflammatory diseases. Regulations vary by country, but in many parts of Asia, Ibuprofen can be purchased without a prescription, enhancing its popularity.
  • Africa: The availability and use of Ibuprofen in African countries vary widely due to different healthcare infrastructure and regulatory environments. In more urbanized areas and regions with better pharmacy access, such as South Africa and Egypt, Ibuprofen is a common and popular choice for pain relief.
  • Australia: In Australia, Ibuprofen is widely used and available over the counter in various formulations, making it popular for its convenience and effectiveness in managing everyday pain and inflammation.

See also  Novovartalon (Glucosamine Sulfate, Meloxicam)

Dosages

Typical dosages of Ibuprofen for adults range from 200 to 800 mg per dose, taken every 6 to 8 hours depending on the strength of the preparation and the severity of symptoms. It’s important not to exceed the maximum recommended daily dosage, which is generally 3200 mg.

Side Effects

Common side effects of Dolprofen may include:

  1. Upset stomach
  2. Heartburn
  3. Nausea
  4. Vomiting
  5. Diarrhea
  6. Dizziness
  7. Headache
  8. Ringing in the ears (tinnitus)
  9. Mild allergic reactions such as rash or itching

Serious side effects requiring immediate medical attention may include:

  1. Severe stomach pain or cramping
  2. Black, tarry stools
  3. Vomit that looks like coffee grounds
  4. Difficulty breathing or wheezing
  5. Swelling of the face, lips, tongue, or throat

Overdose

In case of overdose with Dolprofen, individuals may experience symptoms such as nausea, vomiting, stomach pain, dizziness, drowsiness, headache, blurred vision, ringing in the ears, seizures, and coma. Overdose can be life-threatening, and immediate medical attention should be sought. Treatment may involve supportive measures to manage symptoms and, if necessary, gastric lavage or administration of activated charcoal to reduce absorption.

Contraindications

Dolprofen is contraindicated in individuals with:

  1. Known hypersensitivity or allergy to ibuprofen or any of the inactive ingredients in the medication
  2. History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  3. Active peptic ulcer disease or a history of gastrointestinal bleeding
  4. Severe heart failure
  5. Severe kidney impairment
  6. Severe liver impairment
  7. Third trimester of pregnancy
  8. History of stroke or heart attack
  9. Before or after coronary artery bypass graft surgery (CABG)

Interactions

Dolprofen may interact with:

  1. Other NSAIDs, including aspirin, increasing the risk of gastrointestinal bleeding and other adverse effects
  2. Anticoagulants (blood thinners) such as warfarin, increasing the risk of bleeding
  3. Corticosteroids, increasing the risk of gastrointestinal ulcers and bleeding
  4. Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), increasing the risk of bleeding
  5. Lithium, increasing the risk of lithium toxicity
  6. Methotrexate, increasing the risk of methotrexate toxicity

See also  Calcort (Deflazacort)

It is crucial to inform healthcare providers about all medications, supplements, and herbal products being taken to avoid potential interactions and ensure safe and effective treatment.