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Oxitraklin (Oxytetracycline)

Active Ingredient: Oxytetracycline
Dosage: 500 mg
Route of Administration: Oral
Dosage Form: Capsules
Quantity per package: 16 capsules per pack

Oxitraklin is a broad-spectrum antibiotic, which is active against a wide variety of Gram-positive and Gram-negative organisms. The drug works by interfering with the ability of bacteria to produce essential proteins. This antibiotic is used to treat infections of the respiratory tract (pneumonia), urinary tract, soft tissues, and skin. It is also used to treat acne, flare-ups of chronic bronchitis, other rarer infections.

Oxitraklin is currently unavailable but you can order an analog of this medicine.


Oxitraklin is indicated in generalized or localized infections caused by germs sensitive to this antibiotic, including rickettsias, mycoplasmas, agents producing psittacosis, ornithosis, lymphogranuloma venereum, inguinal granuloma and recurrent fever, infections by certain gram-negative germs, including brucellosis, germs gram-positive and others.

Oxytetracycline is indicated in:

  • Bronchopulmonary infections, such as pneumonia, bronchitis and processes that occur with an emetic cough (which causes vomiting);
  • Sexually transmitted diseases, such as chlamydia, gonorrhea or syphilis;
  • Urinary tract infections;
  • Skin infections, such as acne;
  • Eye infections, such as conjunctivitis;
  • Rickettsiosis, such as Q fever or fever caused by ticks (buttony fever);
  • Other infections, including brucellosis (Malta fever), psittacosis, plague, cholera, leptospirosis, gas gangrene and tetanus.

Consult your doctor before using this antibiotic.

Dosage and administration

These tablets should be taken on an empty stomach, which means one hour before the meal or two hours after the meal. Do not take the tablets at the same time as food, milk or dairy products, as they can prevent the medication from being properly absorbed by the body and make it less effective.

Swallow the tablets whole with plenty of water while sitting or standing to prevent the medicine from irritating the throat. Avoid taking a dose before bedtime. Do not take indigestion remedies or medications that contain aluminum, calcium, iron, magnesium or zinc within two hours before or after taking oxytetracycline tablets. These can reduce the absorption of oxytetracycline from the intestine and make it less effective.

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If you forget to take a dose of oxytetracycline, take it as soon as you remember unless it is almost time for your next dose. In this case, skip the missed dose and take the next dose as usual. Do not take a double dose to make up for the missed dose.

The dose and duration of treatment vary depending on your disease. To treat acne and rosacea: a typical dose is 500 mg (two tablets) twice a day, morning and afternoon. For rosacea, you will need to take it for 6 to 12 weeks. For acne, you should continue treatment for at least three months. Follow the instructions given by your doctor.

To treat infections, take one or two tablets four times a day. Take your doses evenly spaced throughout the day, every six hours. The dose and duration of treatment depend on the type and severity of your infection. Always follow your doctor’s instructions.

End the prescribed cycle of the antibiotic even if you feel better or it seems that the infection has healed. Treatment interruption increases the chances of the infection coming back and the bacteria becoming resistant to the antibiotic.


Do not take this medicine if you are allergic (hypersensitive) to oxytetracycline or other tetracyclines, including minocycline and doxycycline. If you think you may be allergic, consult your doctor.

Allergy symptoms may include:

  • asthma crisis, with breathing difficulties, breathing with audible whistles or rapid breathing;
  • sudden swelling of the face, lips, tongue or other place of the body (angioedema). It is especially critical if it affects the vocal cords;
    hives, itching, rash;
  • anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

You should also not take this medicine if:

  • you have major kidney or liver disorders;
  • you have generalized lupus erythematosus;
  • you are under the age of 12 years.

Warning: The use of tetracyclines during the development phase of the teeth can cause damage to the tooth enamel with an alteration of the color of the tooth, which turns a yellowish-brown color irreversibly. This can happen during the formation of the fetal teeth in the second half of pregnancy and during the first eight years of childhood. The risk increases with prolonged treatment. Cases of enamel hypoplasia have also been observed by exposure to a tetracycline during tooth formation.

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As indicated, this medicine (or another tetracycline) should not be administered during the dental formation phase, except in the case that the doctor considers that no other effective medicine is available or the alternative drug is clearly contraindicated.

Take Oxitraklin with caution:

  • if you suffer from myasthenia gravis (disease that causes marked muscle weakness and other symptoms);
  • if you have a decrease in liver or kidney function.

Patients with some degree of renal insufficiency may experience urea elevation and other alterations as a result of taking tetracyclines.

Side effects

Like all medicines, Oxitraklin can have side effects, although not every patient gets them.

The active substance oxytetracycline is generally well tolerated, although occasionally it can lead to stomach upset, which is not usually a reason for treatment discontinuation. Rarely, you may experience glossitis, stomatitis, diarrhea, vaginitis, proctitis and fungal growth (candidiasis).

Tell your doctor if you have any of the following side effects:

  • Sensation of discomfort, diarrhea, abdominal pain, loss of appetite, changes in tooth enamel color, difficulty swallowing, inflammation or ulcer of the throat;
  • Symptoms of possible pseudomembranous colitis: liquid diarrhea, fever and abdominal cramps;
  • Symptoms of possible inflammation of the pancreas (pancreatitis), with pain in the abdomen or back, feeling sick and fever;
  • Alteration in the number and type of blood cells (leukocytes, platelets, red blood cells). If you have bruises without cause to explain it or an unexpected increase in them, nosebleeds, sore throat, infections, excessive tiredness, shortness of breath, or abnormal skin paleness, you should inform your doctor as soon as possible;
  • Redness or change in skin color, scaly skin, thrush or irritation around the genitals and adjacent areas. If you already suffer from generalized lupus erythematosus, this medicine may make the disease worse;
  • Impaired renal or hepatic function, with fatigue, pain in the abdomen or back, difficulty urinating or jaundice (yellowing of the skin or whites of the eyes).
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If you observe any other reaction not described on this website or in the leaflet that accompanies the package, consult your doctor or pharmacist.
If you think that any of the side effects you suffer is serious, tell your doctor or pharmacist.


In cases of overdose, respiratory control is suggested by maintaining adequate ventilation, control of vital signs, administration of activated carbon, induced emesis, gastric lavage.


Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or medicines obtained without a prescription. Especially:

  • Penicillin;
  • Vitamin A;
  • Retinoids, such as acitretin, tretinoin and isotretinoin, medicines to treat acne;
  • Oral contraceptives (loss of contraceptive effectiveness). It is advisable to use an alternative method of contraception up to at least one week after stopping treatment with this antibiotic;
  • Anticoagulant medicines such as acenocoumarol and warfarin, as Oxitraklin depresses activity;
  • Diuretics, such as furosemide;
  • Kaolin-pectin and bismuth subsalicylate (medicines for the treatment of diarrhea);
  • Antidiabetic medicines such as insulin and oral antidiabetic medicines (glibenclamide, gliclazide);
  • Methoxyflurane (an anesthetic). If you are going to have surgery or have dental surgery tell your doctor or dentist that you are taking oxytetracycline tablets;
  • Antacids or medicinal products containing salts of aluminium, calcium, iron or magnesium, bismuth or zinc. It is not recommended to take these compounds together with Oxitraklin, as absorption of the antibiotic may be reduced. Leave an interval of two or three hours between taking the antacid and taking oxytetracycline;
  • Medicines such as oxytetracycline (bacteriostatic, that is, which inhibit the growth of bacteria) can interfere with bactericidal antibiotics (which destroy bacteria), such as penicillins. It is not advisable to take both types of antibiotics together.