Active Ingredient: Metoclopramide, Aluminum, Magnesium, Simethicone
Dosage: 10 mg/200 mg/200 mg/50 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 20 tablets per pack
Pramigel is a combination of metoclopramide, aluminum, magnesium and simethicone. The drug has gastroprokinetic, antiemetic, demulcent and antiflatulent activity. It is indicated in acute and chronic gastritis, esophagitis due to gastroesophageal reflux, gastroduodenal ulcer, hiatal hernia, dyspepsia, aerophagia, meteorism, aerocolia, excess of food accompanied by gastric hyperacidity and in hyperchlorhydria and other disorders that respond favorably to the administration of a gastroprokinetic associated with a combined antacid and an antiflatulent. It is also indicated in the treatment of nonspecific dyspepsia in children and adults; migraine and headache.
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This drug is indicated in acute and chronic gastritis, gastroesophageal reflux esophagitis, gastroduodenal ulcer, hiatal hernia, dyspepsia, aerophagia, meteorism, aerocolia accompanied by gastric hyperacidity and hyperchlorhydria and other disorders that respond favorably to the administration of a gastroprokinetic associated with a combined antacid and an antiflatulent. It is also indicated in the treatment of nonspecific dyspepsias in children and adults. It is useful in the treatment of migraines and headaches.
Dosage and administration
The drug is taken orally. Children from 6 to 12 years: ½ tablet every 8 hours. Children over 12 years and adults: 1 tablet every 8 hours.
- Hypersensitivity to any of the formula’s components;
- Active gastrointestinal bleeding;
- Intestinal occlusion;
- Pancreatitis or acute appendicitis;
- Renal or hepatic impairment;
- Hypersensitivity to any of the compounds of the formula.
Sensitive patients can experience drowsiness and laxity, insomnia, dizziness, mild extrapyramidal symptoms, gynecomastia and hives. These symptoms disappear when the dose is adjusted or when the administration is suspended.
When accidental Pramigel overdose occurs, patients may experience sedation, dizziness, extrapyramidal reactions such as torticollis, trismus, oculogyric crises, constipation or diarrhea. These adverse effects are reversible when the dose is reduced or the medication is canceled.
When metoclopramide is concomitantly administered with psychotropic, antihistamines, barbiturates or alcohol, it produces additional depressive effects on the CNS. Chloramphenicol, acetylsalicylic acid, desipramine, doxorubicin and propantheline decrease the absorption rate of metoclopramide. Do not administer the drug with digitalis, phenothiazines, propranolol.