Prazolan (Pantoprazole)

Active Ingredient: Pantoprazole
Dosage: 20, 40 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 7, 14, 28 tablets per pack

Prazolan is a proton-pump inhibitor that can treat gastroesophageal reflux disease (GERD). It is also indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. It can also treat high levels of stomach acid caused by tumors.

Prazolan is currently unavailable in the store but you can buy its complete analog.

Indications

Prazolan is used to treat:

• peptic ulcer;
• reflux disease and its symptoms (heartburn, nausea, belching);
• reflux esophagitis (damage to the esophagus caused by reflux of gastric contents);
• ulcers and erosion of the stomach/intestine caused by long-term medication (NSAIDs) in persons at risk;
• Zollinger-Ellison syndrome.

It is also used as part of therapy aimed at eradicating Helicobacter pylori.

Dosage and administration

The tablets are intended for oral use.

Recommended doses (for adults and children over 12 years):

• reflux disease: 20 mg/day for 2–4 weeks;
• esophagitis: 20 mg/day for 4–8 weeks;
• prevention of ulcers and erosion of the stomach/intestine caused by NSAIDs: 20 mg/day;
• reflux esophagitis: 20 mg – 40 mg / day;
• treatment of Zollinger-Ellison syndrome: 80 mg/day for 2 doses (a temporary increase to 160 mg is possible), the duration of treatment is not limited.

Contraindications

Prazolan is contraindicated in case of hypersensitivity to the ingredients of the drug.

Side effects

• Blood test changes: pancytopenia, agranulocytosis, leukopenia, thrombocytopenia;
• Immune system disorders: anaphylactic reactions/shock, Quincke edema;
• Skin changes: alopecia, urticaria, dermatitis, pruritus, rash, erythema multiforme, photosensitivity, Stevens-Johnson syndrome, toxic epidermonecrolysis, lupus erythematosus;
• Metabolic disorders: electrolyte disturbances (hypomagnesemia, hyponatremia, hypokalemia, hypocalcemia);
• Mental and nervous system disorders: paresthesia, taste disturbances, drowsiness, headache, dizziness, aggression, confusion, depression, insomnia, anxiety, hallucinations;
• Perceptual disorders: visual acuity disorder, vertigo;
• Respiratory disorders: bronchospasm;
• Digestive disorders: flatulence, diarrhea/constipation, dry mouth, pain in the pancreas, vomiting, increased levels of AlAT / ASAT, hepatic encephalopathy, hepatitis, jaundice, liver failure;
• Genitourinary disorders: gynecomastia (breast enlargement), interstitial nephritis;
• Common disorders: fever, malaise, sweating, swelling.

Overdose

There is no evidence of an overdose of pantoprazole. In studies, when the drug was administered at a dose of 240 mg, no negative effects occurred. In case of symptoms of poisoning, general measures are taken to accelerate the elimination of the drug from the body. Maintenance therapy is prescribed.

Interaction

No clinically significant interactions were detected.