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Robaxifen (Methocarbamol, Acetaminophen)

Active Ingredient: Methocarbamol, Acetaminophen
Dosage: 400 mg/350 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 24 tablets per pack

Robaxifen is an analgesic-antipyretic. The dug contains methocarbamol and acetaminophen (paracetamol). It can relieve pain with a skeletal muscle spasm in any region of the locomotor system. It is prescribed to treat headache, migraine, neuralgia, myalgia, algomenorrhea, toothache, pain in trauma, burns, fever in infectious and inflammatory diseases. Currently, this drug is unavailable. Please, get acquainted with its analog here.


Robaxifen is indicated in physiotherapy and other measures to relieve discomfort associated with acute painful musculoskeletal conditions. The mode of action of Methocarbamol has not been clearly explored but could be related to sedative properties. Methocarbamol does not directly relax the muscles with active contraction in man.

Dosage and administration

Route of administration: oral. Dose: adults and children over 12 years old: 2 tablets 3 times a day. Do not administer in children under 12 years old.


Hypersensitivity to any of the drug components.

Side effects

The most common side effects of Robaxifen are dizziness, faintness, and nausea. These side effects occur in approximately 4-5% of patients. Other less frequent reactions are:

  • drowsiness;
  • blurred vision;
  • headache;
  • fever;
  • allergic manifestations such as hives, itching, and rash.

Adverse reactions that have been associated with the use of paracetamol include:

  • dermatological reactions (skin rash and hives);
  • neutropenia;
  • thrombocytopenic purpura.

Rarely, laryngeal edema, angioedema, anaphylaxis, and agranulocytosis have been detected.


The information available on the acute toxicity of Robaxifen is limited. There are no definite cases recorded.

See also  Voveran SR (Diclofenac)


Robaxifen should be used with caution in patients with myasthenia gravis who are receiving anticholinesterase agents. This drug administered concomitantly with phenothiazine can cause severe hypothermia.