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Rodogyl (Spiramycin, Metronidazole)

Active Ingredient: Spiramycin, Metronidazole
Dosage: 750.000 UI/125 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 20 tablets per pack

Rodogyl is a broad-spectrum antibiotic that is used to treat bacterial infections of the vagina, stomach or intestines, liver, skin, joints, brain, heart, and respiratory tract. It works by stopping the growth of certain bacteria and parasites. Rodogyl may also be used with other drugs to treat stomach/intestinal ulcers caused by bacteria.

Rodogyl is currently out of stock but there are many other similar antibiotics on this page.


Acute, chronic or relapsing stomatological infections:

  • Dental abscesses, phlegmon, premaxillary cellulitis, pericoronitis;
  • Stomatitis;
  • Periodontitis;
  • Preventive treatment of postoperative local infectious complications in odontostomatologic surgery.

Dosage and administration

The drug is taken orally. The tablets should be swallowed with a full glass of water during the meal.

  • Adults: 4-6 tablets per day in 2 or 3 doses. In severe cases, the dosage may be increased to 8 tablets per day;
  • Children: From 6 to 10 years: 2 tablets per day; 10 to 15 years: 3 tablets per day.

There is uncertainty about the optimal dose of this medication. Consult your doctor before use.


  • Hypersensitivity to spiramycin;
  • Hypersensitivity to metronidazole;
  • Hypersensitivity to imidazole;
  • Children under 6 years;
  • G6PD deficiency;
  • Breastfeeding;
  • Alcohol consumption;
  • Cockayne syndrome.

Side effects

  • Digestive disorders: Gastralgias, nausea, vomiting, diarrhea, and very rare cases of pseudomembranous colitis;
  • Skin and allergic manifestations: rashes, hives, pruritus; rarely, Quincke’s edema, anaphylactic shock;
  • Central and peripheral nervous system: Occasional and transient paresthesias;
  • Hepatic manifestations: Very rare cases of liver function abnormalities;
  • Immune system disorders: angioedema, anaphylactic shock;
  • Psychiatric disorders: psychotic disorders, including confusion, hallucinations, depressive mood;
  • Eye disorders: transient visual disorders such as diplopia and myopia, blurred vision, decreased visual acuity, changes in color vision, optic neuropathy/neuritis;
  • Disorders in the lymphatic system and blood: cases of agranulocytosis, neutropenia and thrombocytopenia have been reported;
    Hepatobiliary disorders: cholestasis or mixed hepatitis and hepatocellular damage, sometimes with jaundice, liver failure;
  • Skin and subcutaneous tissue disorders: erythema, pruritus, blushing, hives, pustular eruptions;
  • General disorders: fever;
  • Blood system: acute hemolysis.


In case of an overdose, call your local emergency services or go to your nearest emergency room.


Rodogyl may interact with the following drugs:

  • Anticoagulant;
  • Phenytoin;
  • Lithium;
  • Disulfiram;
  • Ciclosporin.

The list is incomplete. Consult your doctor.