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Senosidos A-B (Sennosides A-B)

Active Ingredient: Sennosides A-B
Dosage: 187 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 20 tablets per pack
Availability: Out of stock

Senosidos A-B is an oral laxative that treats mild constipation, caused by bad eating habits, lack of exercise and insufficient intake of natural fiber. It is also used in cases of colonoscopies and sigmoidoscopy, in the preparation of the patient for anorectal surgeries.

Senosidos A-B is out of stock but you can choose from other laxatives online.

Indications

Senosidos A-B is a natural laxative of plant origin for the treatment of mild constipation caused by poor eating habits, lack of exercise and inadequate intake of natural fiber.

The drug is also used to:

  • relieve evacuation pain in patients with episiotomy wounds, thrombosed hemorrhoids, anal fissures or perianal abscesses;
  • facilitate elimination and reduce excessive intra-abdominal effort and pressure in patients with diaphragmatic or abdominal wall hernias, anorectal stenosis, aneurysm and other diseases of the cerebral and coronary arteries;
  • relieve constipation during pregnancy and postpartum;
  • prevent or decrease the absorption of ammonium and other neurotoxins in patients with hepatic encephalopathy;
  • prepare the intestine for surgical or radiological procedures;
  • provide a fresh evacuation for coproparasitoscopic exams;
  • accelerate the excretion of various parasites including nematodes after an anthelmintic therapy;
  • accelerate the excretion of poisons ingested orally;
  • modify the evacuations of patients with ileostomy or colostomy.

The drug is also used in geriatric patients with an inadequate intake of fiber and whose abdominal walls and perianal muscles have lost their tone; in patients with severe neuromuscular diseases; in children with acquired or congenital megacolon; when intestinal motility has been altered by other medications such as anticholinergics or opioids.

The drug is particularly useful in patients with acute constipation, in geriatric patients with poor eating habits or weak abdominal muscles. Some studies indicate the efficiency of these tablets for the treatment of childhood encopresis.

Dosage and administration

For oral use.

  • Teenagers and adults: 1-2 tablets before bedtime.
  • Pregnancy: Half the dose is recommended.

Contraindications

Senosidos A-B is contraindicated for use in patients with hydroelectrolytic imbalance, appendicitis, abdominal pain, nausea and vomiting. Fecal impaction and intestinal obstruction or perforation are also contraindications because the medication can make symptoms worse.

Side effects

The adverse reactions that have been reported after taking Senosidos A-B are: nausea, vomiting, diarrhea, loss of normal bowel function (when used excessively), colic pain (especially in severe constipation), nutrient malabsorption, cathartic colon in chronic use, constipation after catharsis, yellow or yellow-greenish stools, diarrhea in children of nursing mothers taking the medication, dark pigmentation of the rectal mucosa when used in the long term (which is reversible in a period of 4 to 12 months ). Besides, a reddish coloration can be found in alkaline urine or yellow-brown in acidic urine.

Some patients have experienced hypokalemia, protein enteropathy and electrolyte imbalance with excessive use. The loss of intrinsic innervation and atrophy of the smooth muscle layer has been reported.

Overdose

When there is long-term abuse of the drug, melanotic pigmentation of the colonic mucosa (melanosis coli) can occur, which is benign and reverses between 4-12 months after the medication is discontinued.

Interaction

  • It can be combined with psyllium with or without mineral oil to prevent constipation in patients at risk or in those who cannot tolerate it due to weakness or disease;
  • The addition of these tablets to psyllium produces a more abundant evacuation than with psyllium alone;
  • Mixtures with docusate salts may be less useful because they increase the absorption of the breast.
  • No other interactions are found.