Solutina F (Pheniramine, Naphazoline)
Active Ingredient: Pheniramine, Naphazoline
Dosage: 3.0 mg/0.25 ml.
Route of Administration: Ocular
Dosage Form: Solution
Quantity per package: 1 unit
Availability: Out of stock
Why Solutina F Is Not Used in the USA
Solutina F is not available in the USA primarily due to FDA regulations and the availability of alternative treatments that are widely accepted and used. The U.S. has strict approval processes for medications, and many other antihistamine and decongestant combinations are already marketed and prescribed.
Eye Drops for Various Conditions Available in the USA
What is Solutina F?
Solutina F is an eye drop indicated for symptomatic temporary relief of mild eye irritation, redness and congestion due to external factors, such as dust, pollution, pool water, etc. It is used to treat visual fatigue, blepharitis, conjunctivitis of different etiologies. The drug combines the antihistamine effects of pheniramine with the vasoconstrictive effects of naphazoline. Naphazoline hydrochloride is a sympathomimetic receptor agonist that produces vasoconstriction. Pheniramine maleate is an H receptor antagonist, which produces antihistaminic effects. Currently, this drug is unavailable.
Indications
This drug is used for:
- eye irritation and/or hyperemia;
- allergic and inflammatory eye diseases.
Where is Solutina F Used?
Solutina F is popular in several countries outside the United States, particularly in:
- Latin America: Countries like Mexico and Brazil, where environmental factors such as pollution and allergens are prevalent.
- Asia: Regions with high pollution levels and dense populations, leading to higher incidences of eye irritations and allergies.
In these regions, Solutina F is favored for its effective relief of symptoms associated with eye allergies and irritations, including redness, puffiness, and itchiness. Its accessibility and effectiveness make it a popular choice.
Dosage and administration
This drug is put into the conjunctival sac of each eye. Recommended dosages are 1-2 drops every 3-4 hours. The drug is used until the symptoms disappear completely. It is advisable to use the minimum effective dosages as soon as possible.
Contraindications
This drug is contraindicated in cases when the patient has a pronounced hypersensitivity (allergy) to the main components or one of the excipients.
It is also contraindicated in angle-closure glaucoma.
Be cautious in the following cases:
- severe diseases of CVS;
- bronchial asthma;
- diabetes mellitus.
Naphazoline nitrate has the property of decreasing the activity of antihypertensive drugs and slowing down the absorption of anesthetics. Not applicable in pediatrics until the age of 12.
Side effects
The drug is usually well tolerated. In the first few minutes after application, mydriasis is noted, which quickly passes.
Side effects may occur in the form of:
- hypersensitivity reactions, including angioedema;
- rash, allergic urticaria, itching;
- dry eyes, burning, reactive hyperemia, swelling of the mucosa;
- depression, loss of consciousness, coma;
- weakness, tremor, nausea, headache, irritability, excessive sweating;
- increased intraocular pressure, hypertension, cardiac arrhythmia, hyperglycemia.
Overdose
In case of accidental excessive intake of the drug, there may occur:
- increase in blood pressure, tachycardia;
- headache, tremor, irritability;
- cyanosis, nausea, cramps;
- cardiac arrest, pulmonary edema;
- drowsiness, bradycardia, shock, apnea, coma.
Discontinue therapy and consult a doctor for emergency assistance in the case of an overdose.
Interaction
Use the drug with caution in patients who are treated with MAO inhibitors. In the case of concomitant therapy using the remaining local ophthalmic preparations, an interval of 5-10 minutes between their use should be followed.