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Tafirol Flex (Chlorzoxazone, Paracetamol)

Active Ingredient: Chlorzoxazone, Paracetamol
Dosage: 300 mg/250 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 30
Availability: Out of Stock

Why Tafirol Flex Is Not Used in the USA

The use of Tafirol Flex in the USA is limited due to FDA regulations concerning the safety and efficacy of drug combinations. Chlorzoxazone as a muscle relaxant has limited popularity in the U.S., and concerns about liver toxicity associated with Paracetamol use at high doses or in combination with other medications might also contribute to its limited use. The U.S. market favors more strictly regulated drugs with clear benefits over potential risks.

Equivalent Drugs Sold in the USA

For treating muscle pain and spasms

For similar symptoms of muscle pain and spasms treated by Tafirol Flex, here are some alternatives used in the United States:

See also  Donodol (Clonixin)

These medications are commonly prescribed in the United States and are approved for their effectiveness in treating conditions related to muscle pain and spasms, providing patients with safe and regulated options for symptom management.

What is Tafirol Flex?

Tafirol Flex is a combination of chlorzoxazone (muscle relaxant) and paracetamol (analgesic and antipyretic). It is used to relieve pain accompanied by spasm of the skeletal muscle due to dislocations, sprains, myalgias, torticollis, tension headache, traumatic muscle damage, lumbago, spondyloarthritis, cervical syndrome.


The typical dosage for Tafirol Flex involves taking one tablet three times a day, though this can vary based on the severity of symptoms and the specific advice of a healthcare provider. It is generally recommended that patients adhere to the prescribed dosage to avoid potential side effects, particularly liver damage from excessive intake of Paracetamol.

Where is Tafirol Popular

Tafirol Flex is particularly popular in countries with less stringent regulations on combination pain relievers, including:

  • Latin America: Countries like Argentina, Mexico, and Brazil where there is high demand for over-the-counter medications for musculoskeletal pain.
  • Some Asian Countries: In nations like the Philippines and India, where accessibility to a range of pain relief options may be limited, Tafirol Flex offers a valuable and effective solution.

In these areas, Tafirol Flex is favored for its rapid relief of muscle pain and spasms, conditions frequently encountered in populations engaged in extensive physical labor. Additionally, the ability to purchase this medication over the counter in many of these countries enhances its appeal, as it allows individuals to access prompt pain relief without the requirement for a prescription from a healthcare professional.

See also  Antidol (Paracetamol)

Side Effects

  • Common Side Effects: These may include drowsiness, dizziness, headache, and upset stomach.
  • Less Common Side Effects: Rare side effects might include allergic reactions like rash, itching, or swelling, as well as liver toxicity symptoms such as dark urine or yellowing of the skin or eyes.


Overdose of Tafirol Flex can lead to severe liver damage due to the high paracetamol content. Symptoms may include nausea, vomiting, abdominal pain, and jaundice. Immediate medical attention is necessary in case of suspected overdose.


  • Liver Disease: Tafirol Flex is contraindicated in individuals with severe liver impairment due to the paracetamol component, as it can exacerbate existing liver damage.
  • Hypersensitivity: Patients with known hypersensitivity to Chlorzoxazone, Paracetamol, or any other ingredients in the formulation should avoid Tafirol Flex.


  • Alcohol: Concurrent use of alcohol with Tafirol Flex may increase the risk of liver toxicity due to the paracetamol content. It’s advisable to avoid alcohol while taking this medication.
  • Central Nervous System Depressants: Tafirol Flex may potentiate the sedative effects of central nervous system depressants such as benzodiazepines or opioids, leading to increased drowsiness or respiratory depression.
  • Warfarin and Anticoagulants: Paracetamol may potentiate the effects of warfarin and other anticoagulant medications, increasing the risk of bleeding. Close monitoring of coagulation parameters is recommended when using Tafirol Flex concomitantly with anticoagulants.

As always, it’s essential to consult with a healthcare professional before starting any new medication, especially if there are concerns about potential interactions or contraindications.