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Barmicil Compuesto Cream (Clotrimazole, Gentamicin, Betamethasone)

Active Ingredient: Clotrimazole, Gentamicin, Betamethasone
Dosage: 1000 mg/100 mg/50 mg
Route of Administration: Local
Dosage Form: Cream
Quantity per package: 2, 4, 6, 12 tubes
Availability: Out of Service

Why Barmicil Compuesto Cream Is Not Used in the USA

Barmicil Compuesto Cream is not used in the USA primarily due to stringent FDA regulations that govern the combination of such potent ingredients in one formulation. The FDA often requires detailed evidence of safety and efficacy for each combination, and there may be concerns about the overuse of antibiotics and steroids, potential resistance development, and side effects from long-term steroid use.

Equivalent Drugs Sold in the USA

For similar symptoms of skin diseases treated by Barmicil Compuesto Cream, here are some drugs for inflammatory skin conditions available in the United States:

This medication in the U.S. offers targeted treatment for fungal, bacterial, and inflammatory skin conditions, providing effective relief while adhering to regulatory standards that ensure their safety and efficacy for patient use.

What is Barmicil Compuesto Cream?

Barmicil Compuesto Cream is prescribed for the relief of inflammatory symptoms of dermatoses. These symptoms are responsive to steroids complicated by a secondary infection. The infection can be caused by organisms sensitive to the components of this dermatologic preparation.

This topical medication contains Clotrimazole, Gentamicin, and Betamethasone. This combination effectively addresses multiple aspects of skin conditions:

  • Clotrimazole is an antifungal agent that helps in treating fungal infections of the skin.
  • Gentamicin is an antibiotic that treats bacterial infections, preventing their growth on the skin.
  • Betamethasone is a corticosteroid that reduces inflammation, redness, and swelling associated with various dermatoses.

See also  Sporanox (Itraconazole)


Barmicil Compuesto Cream is used to treat dermatoses complicated by infections caused by pathogens susceptible to the drug, or with suspected infections such as:

  • simple and allergic dermatitis;
  • atopic dermatitis (including diffuse neurodermatitis);
  • limited neurodermatitis;
  • eczema;
  • dermatomycoses (dermatophytosis, candidiasis), especially when localized in the inguinal region and large folds of the skin;
  • simple chronic lichen (limited neurodermatitis).

Where Is Barmicil Compuesto Cream Used?

Barmicil Compuesto Cream is popular in several countries, particularly in:

  • Latin America: Countries like Mexico and others in Central and South America where climatic conditions can exacerbate skin conditions, making multi-faceted topical treatments like Barmicil Compuesto Cream valuable.
  • Parts of Asia: Similar use patterns are seen in Asian countries where there is high humidity and heat, contributing to skin issues.

In these regions, the combination of an antifungal, antibiotic, and anti-inflammatory agent in one cream provides a comprehensive treatment that is highly valued for its effectiveness. This is particularly useful in areas with limited access to a wide range of medical treatments or where polypharmacy (using multiple medications) is common.

Dosage and administration

The cream is applied locally.

A small amount of the drug is applied to the affected areas of the skin, 2 times a day. The duration of treatment is determined individually and depends on the nosological form and severity of the disease.

With dermatomycosis of the feet, the average duration of treatment is 2–4 weeks.

If clinical improvement does not occur in the near future, it is necessary to clarify the diagnosis or change the treatment regimen.


Do use Barmicil Compuesto Cream if you have any of the following conditions/diseases:

  • hypersensitivity to any of the components of the drug;
  • lupus;
  • skin manifestations of syphilis;
  • chickenpox;
  • herpes simplex;
  • skin post-vaccination reactions;
  • open wounds;
  • children under the age of 2 years.

See also  Gelmicin (Betamethasone; Clotrimazole)

Precautions: pregnancy (especially in the first trimester); children’s age (> 2 years); long-term treatment; application on large areas of the skin or in violation of the integrity of the skin; the use of occlusive dressings (especially in children).

Side effects

In some cases, the cream can cause itching, burning, irritation, dry skin, folliculitis, hypertrichosis, steroid acne, hypopigmentation, allergic reactions.

When using occlusive dressings — a person can experience maceration, infection, atrophy of the skin, striae, prickly heat.

With prolonged treatment or application to a large surface, the drug can cause systemic side effects: weight gain, osteoporosis, increased blood pressure, swelling, ulceration of the gastrointestinal mucosa, exacerbation of hidden foci of infection, hyperglycemia, agitation, insomnia, dysmenorrhea.


The prolonged use of this cream in high doses can cause secondary adrenal insufficiency and symptoms of hypercorticism, including Cushing’s syndrome.

An overdose of clotrimazole with its local use does not cause any symptoms.

A single overdose of gentamicin does not cause any symptoms. Long-term treatment with high doses of gentamicin can lead to the growth of insensitive flora.

Treatment should be symptomatic. The acute symptoms of hypercorticism are usually reversible. If necessary, electrolyte imbalance is corrected. In the case of chronic corticosteroid toxicity, gradual cancellation of corticosteroids is recommended.


Clinically significant interactions are unknown.