Reumophan-Vit (Chlorzoxazone, Ketoprofen)

Active Ingredient: Chlorzoxazone, Ketoprofen
Dosage: 250 mg/50 mg
Route of Administration: Oral
Dosage Form: Chewable tablets
Quantity per package: 20 tablets per pack
Availability: Out of stock

Reumophan-Vit is a muscle relaxant and analgesic that is used to treat antineuritic rheumatoid arthritis, osteoarthritis, polyneuropathy, neuralgia, radiculopathy, painful vertebral syndromes, lumbalgia, lumbosciatica, sciatic neuritis, arthralgias, muscle spasms. The drug contains chlorzoxazone and ketoprofen.

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Indications

• Rheumatoid arthritis;
• Osteoarthritis;
• Polyneuropathy, neuralgia, radiculopathy;
• Painful vertebral syndromes;
• Low back pain, lumbociática, sciatica neuritis;
• Arthralgias;
• Muscle spasms.

Dosage and administration

Take one tablet every 6 to 12 hours depending on the severity of the symptoms.

Contraindications

• Hypersensitivity to the components of the formula,
• Rhinitis,
• Urticaria,
• Asthma.

Side effects

Reumophan-Vit can cause dyspepsia and other gastrointestinal adverse effects. They are usually mild and decrease if the drug is taken with food, milk or antacids. It can also cause fluid retention and higher plasma creatinine concentrations, which are transient and occur without symptoms. It can also cause drowsiness, dizziness, discomfort and overstimulation.

Overdose

The symptoms of chlorzoxazone overdose can be stupor, coma, shock, respiratory depression. The symptoms of ketoprofen overdose can be drowsiness, heartburn, nausea and vomiting.

Interaction

Oral anticoagulants require close monitoring of coagulation parameters. The use of alendronate has been associated with gastrointestinal irritation, so this effect can be increased with concomitant administration. NSAIDs may decrease the antihypertensive and natriuretic effects. Simultaneous use of ketoprofen and aspirin may produce reduced serum levels of ketoprofen, but the clinical importance of this observation is undetermined. The coexisting use of beta-adrenergic blocker NSAIDs may cause an increase in blood pressure. This effect has been reported for flurbiprofen (400 mg daily), ibuprofen (more than 400 mg daily), indomethacin (more than 50 mg daily), naproxen (1,000 mg daily) and piroxicam.