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Reumophan-Vit (Chlorzoxazone, Ketoprofen)

Active Ingredient: Chlorzoxazone, Ketoprofen
Dosage: 250 mg/50 mg
Route of Administration: Oral
Dosage Form: Chewable tablets
Quantity per package: 20 tablets per pack
Availability: Out of stock

Why Does Reumophan-Vit Lack in the USA?

Reumophan-Vit is not used in the USA primarily because it has not been approved by the U.S. Food and Drug Administration (FDA). The FDA requires rigorous testing and proof of efficacy and safety, which Reumophan-Vit might not have undergone to the standards required by U.S. regulations.

What are the alternative options of Reumophan-Vit in the USA?

Here are similar drugs available in the USA that are used to treat the same diseases and symptoms as Reumophan-Vit, categorized based on their primary functions as muscle relaxants and NSAIDs:

Muscle Relaxants:

NSAIDs for Pain and Inflammation:

See also  Dioxaflex Duo (Diclofenac, Pridinol)

Combination Therapies:

What is Reumophan-Vit (Chlorzoxazone, Ketoprofen)?

Reumophan-Vit is a muscle relaxant and analgesic that is used to treat antineuritic rheumatoid arthritis, osteoarthritis, polyneuropathy, neuralgia, radiculopathy, painful vertebral syndromes, lumbalgia, lumbosciatica, sciatic neuritis, arthralgias, muscle spasms. The drug contains chlorzoxazone and ketoprofen. Chlorzoxazone acts as a muscle relaxant, helping to alleviate muscle spasms and discomfort, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and joint stiffness associated with conditions like rheumatoid arthritis and osteoarthritis.


  • Rheumatoid arthritis;
  • Osteoarthritis;
  • Polyneuropathy, neuralgia, radiculopathy;
  • Painful vertebral syndromes;
  • Low back pain, lumbociática, sciatica neuritis;
  • Arthralgias;
  • Muscle spasms.

Widespread Use of Reumophan-Vit in Various Regions

Reumophan-Vit is notably popular in many Latin American countries and certain European regions. Its appeal stems largely from how well it aligns with local medical practices, particularly in treating conditions like arthritis with a combination of Chlorzoxazone and Ketoprofen. The medication is readily available, making it an accessible choice for those in need of relief from musculoskeletal pain. Additionally, its cost-effectiveness makes Reumophan-Vit an economically viable option, which enhances its accessibility and usage among a broad demographic, contributing to its widespread adoption in these areas. This combination of factors ensures Reumophan-Vit remains a primary choice for effectively managing pain and muscle spasms associated with various musculoskeletal disorders.

Dosage and administration

Take one tablet every 6 to 12 hours depending on the severity of the symptoms.

See also  Dioxaflex Duo (Diclofenac, Pridinol)


  • Hypersensitivity to the components of the formula,
  • Rhinitis,
  • Urticaria,
  • Asthma.

Side effects

Reumophan-Vit can cause dyspepsia and other gastrointestinal adverse effects. They are usually mild and decrease if the drug is taken with food, milk or antacids. It can also cause fluid retention and higher plasma creatinine concentrations, which are transient and occur without symptoms. It can also cause drowsiness, dizziness, discomfort and overstimulation.


The symptoms of chlorzoxazone overdose can be stupor, coma, shock, respiratory depression. The symptoms of ketoprofen overdose can be drowsiness, heartburn, nausea and vomiting.


Oral anticoagulants require close monitoring of coagulation parameters. The use of alendronate has been associated with gastrointestinal irritation, so this effect can be increased with concomitant administration. NSAIDs may decrease the antihypertensive and natriuretic effects. Simultaneous use of ketoprofen and aspirin may produce reduced serum levels of ketoprofen, but the clinical importance of this observation is undetermined. The coexisting use of beta-adrenergic blocker NSAIDs may cause an increase in blood pressure. This effect has been reported for flurbiprofen (400 mg daily), ibuprofen (more than 400 mg daily), indomethacin (more than 50 mg daily), naproxen (1,000 mg daily) and piroxicam.